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The Effects of Air Pollution, Sea Exposure and Altitude on COVID-19 Hospitalization Rates in Italy

Early known cases of COVID-19 emerged in late 2019 in the city of Wuhan (China) and in a relatively short time, it has reached more than 200 countries up to July 2020. In Italy, from 21 February 2020, (first official Italian positive case of COVID-19) until 27 July 2020, 246,286 confirmed cases were...

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Autores principales: Cascetta, Ennio, Henke, Ilaria, Di Francesco, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828064/
https://www.ncbi.nlm.nih.gov/pubmed/33430024
http://dx.doi.org/10.3390/ijerph18020452
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author Cascetta, Ennio
Henke, Ilaria
Di Francesco, Luigi
author_facet Cascetta, Ennio
Henke, Ilaria
Di Francesco, Luigi
author_sort Cascetta, Ennio
collection PubMed
description Early known cases of COVID-19 emerged in late 2019 in the city of Wuhan (China) and in a relatively short time, it has reached more than 200 countries up to July 2020. In Italy, from 21 February 2020, (first official Italian positive case of COVID-19) until 27 July 2020, 246,286 confirmed cases were observed of which over 68,150 (28%) needed hospitalization and 35,112 died. In recent scientific research, it has been shown that the severity of symptoms and mortality rates were different not only among the various countries of the world but also in different regions of the same country. This research investigates whether and by how much air environmental conditions (such as exposure to fine particulate matter-PM(2.5), sea air masses and altitude) influences the risk of hospitalization due to COVID-19 in Italy, once the spreading of the virus and the percentage of the elderly in the population have been accounted for. A log-linear multiple regression model was estimated where the log of the ratio of hospitalized patients per inhabitant, since the beginning of the epidemic up to July 27, has been considered as a dependent variable. Among the independent variables, the ones that have been taken into account are the spreading of the virus, the rate of people over 50 years of age, the concentration of PM(2.5), the rate of population living by the sea, the rate of green public space for each resident and the ratio of population living at a high altitude. The results showed an increase in the hospitalization rate in terms of the percentage of people over 50 and the average concentration of PM(2.5). If average limits of PM(2.5) concentration allowed by the current European regulations (25 µg/m(3)) were respected in all Italian provinces, that would have led to 7339 less hospitalizations for COVID-19 (−11%). On the contrary, near the coast there were lower hospitalized cases in the referred period. In the hypothetical case that no Italians lived near the sea, about 1363 (+2%) more hospitalizations would have been recorded in the analysis period in addition to the effect of a lower PM concentration. This paper wanted to investigate which are the areas with a higher risk of hospitalization in Italy, so as to help the Italian Government to strengthen Health System measures, predicting the most suffering areas and health care systems. According to the results, this is directly related to the severity of symptoms which decreased with the long-time exposure to the sea.
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spelling pubmed-78280642021-01-25 The Effects of Air Pollution, Sea Exposure and Altitude on COVID-19 Hospitalization Rates in Italy Cascetta, Ennio Henke, Ilaria Di Francesco, Luigi Int J Environ Res Public Health Article Early known cases of COVID-19 emerged in late 2019 in the city of Wuhan (China) and in a relatively short time, it has reached more than 200 countries up to July 2020. In Italy, from 21 February 2020, (first official Italian positive case of COVID-19) until 27 July 2020, 246,286 confirmed cases were observed of which over 68,150 (28%) needed hospitalization and 35,112 died. In recent scientific research, it has been shown that the severity of symptoms and mortality rates were different not only among the various countries of the world but also in different regions of the same country. This research investigates whether and by how much air environmental conditions (such as exposure to fine particulate matter-PM(2.5), sea air masses and altitude) influences the risk of hospitalization due to COVID-19 in Italy, once the spreading of the virus and the percentage of the elderly in the population have been accounted for. A log-linear multiple regression model was estimated where the log of the ratio of hospitalized patients per inhabitant, since the beginning of the epidemic up to July 27, has been considered as a dependent variable. Among the independent variables, the ones that have been taken into account are the spreading of the virus, the rate of people over 50 years of age, the concentration of PM(2.5), the rate of population living by the sea, the rate of green public space for each resident and the ratio of population living at a high altitude. The results showed an increase in the hospitalization rate in terms of the percentage of people over 50 and the average concentration of PM(2.5). If average limits of PM(2.5) concentration allowed by the current European regulations (25 µg/m(3)) were respected in all Italian provinces, that would have led to 7339 less hospitalizations for COVID-19 (−11%). On the contrary, near the coast there were lower hospitalized cases in the referred period. In the hypothetical case that no Italians lived near the sea, about 1363 (+2%) more hospitalizations would have been recorded in the analysis period in addition to the effect of a lower PM concentration. This paper wanted to investigate which are the areas with a higher risk of hospitalization in Italy, so as to help the Italian Government to strengthen Health System measures, predicting the most suffering areas and health care systems. According to the results, this is directly related to the severity of symptoms which decreased with the long-time exposure to the sea. MDPI 2021-01-08 2021-01 /pmc/articles/PMC7828064/ /pubmed/33430024 http://dx.doi.org/10.3390/ijerph18020452 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cascetta, Ennio
Henke, Ilaria
Di Francesco, Luigi
The Effects of Air Pollution, Sea Exposure and Altitude on COVID-19 Hospitalization Rates in Italy
title The Effects of Air Pollution, Sea Exposure and Altitude on COVID-19 Hospitalization Rates in Italy
title_full The Effects of Air Pollution, Sea Exposure and Altitude on COVID-19 Hospitalization Rates in Italy
title_fullStr The Effects of Air Pollution, Sea Exposure and Altitude on COVID-19 Hospitalization Rates in Italy
title_full_unstemmed The Effects of Air Pollution, Sea Exposure and Altitude on COVID-19 Hospitalization Rates in Italy
title_short The Effects of Air Pollution, Sea Exposure and Altitude on COVID-19 Hospitalization Rates in Italy
title_sort effects of air pollution, sea exposure and altitude on covid-19 hospitalization rates in italy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828064/
https://www.ncbi.nlm.nih.gov/pubmed/33430024
http://dx.doi.org/10.3390/ijerph18020452
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