In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications—A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B

Diabetes mellitus (DM) is a complex disease which currently affects more than 460 million people and is one of the leading cause of death worldwide. Its development implies numerous metabolic dysfunctions and the onset of hyperglycaemia-induced chronic complications. Multiple ligands can be rational...

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Detalles Bibliográficos
Autores principales: Ottanà, Rosaria, Paoli, Paolo, Cappiello, Mario, Nguyen, Trung Ngoc, Adornato, Ilenia, Del Corso, Antonella, Genovese, Massimo, Nesi, Ilaria, Moschini, Roberta, Naß, Alexandra, Wolber, Gerhard, Maccari, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828111/
https://www.ncbi.nlm.nih.gov/pubmed/33435264
http://dx.doi.org/10.3390/molecules26020330

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