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‘Educated’ Osteoblasts Reduce Osteoclastogenesis in a Bone-Tumor Mimetic Microenvironment

SIMPLE SUMMARY: Patients with late-stage bone metastatic breast cancer experience skeletal related events, including osteolytic lesion formation, due to overactive osteoclast bone resorption. It is well-known that osteoclast function is altered by breast cancer cells in bone. Breast cancer cells sti...

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Detalles Bibliográficos
Autores principales: Kolb, Alexus D., Dai, Jinlu, Keller, Evan T., Bussard, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828118/
https://www.ncbi.nlm.nih.gov/pubmed/33445695
http://dx.doi.org/10.3390/cancers13020263