Seeding Propensity and Characteristics of Pathogenic αSyn Assemblies in Formalin-Fixed Human Tissue from the Enteric Nervous System, Olfactory Bulb, and Brainstem in Cases Staged for Parkinson’s Disease

We investigated α-synuclein’s (αSyn) seeding activity in tissue from the brain and enteric nervous system. Specifically, we assessed the seeding propensity of pathogenic αSyn in formalin-fixed tissue from the gastric cardia and five brain regions of 29 individuals (12 Parkinson’s disease, 8 incident...

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Detalles Bibliográficos
Autores principales: Fenyi, Alexis, Duyckaerts, Charles, Bousset, Luc, Braak, Heiko, Tredici, Kelly Del, Melki, Ronald, on behalf of the Brainbank Neuro-CEB Neuropathology Network
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828121/
https://www.ncbi.nlm.nih.gov/pubmed/33445653
http://dx.doi.org/10.3390/cells10010139

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