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Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide

An innovative type of biodegradable thermoplastic elastomers with improved mechanical properties from very common and potentially renewable sources, poly(L-lactide)-b-poly(2-methyl-1,3-propylene glutarate)-b-poly(L-lactide) (PLA-b-PMPG-b-PLA)s, has been developed for the first time. PLA-b-PMPG-b-PLA...

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Autores principales: Zahir, Lamya, Kida, Takumitsu, Tanaka, Ryo, Nakayama, Yuushou, Shiono, Takeshi, Kawasaki, Norioki, Yamano, Naoko, Nakayama, Atsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828133/
https://www.ncbi.nlm.nih.gov/pubmed/33445658
http://dx.doi.org/10.3390/life11010043
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author Zahir, Lamya
Kida, Takumitsu
Tanaka, Ryo
Nakayama, Yuushou
Shiono, Takeshi
Kawasaki, Norioki
Yamano, Naoko
Nakayama, Atsuyoshi
author_facet Zahir, Lamya
Kida, Takumitsu
Tanaka, Ryo
Nakayama, Yuushou
Shiono, Takeshi
Kawasaki, Norioki
Yamano, Naoko
Nakayama, Atsuyoshi
author_sort Zahir, Lamya
collection PubMed
description An innovative type of biodegradable thermoplastic elastomers with improved mechanical properties from very common and potentially renewable sources, poly(L-lactide)-b-poly(2-methyl-1,3-propylene glutarate)-b-poly(L-lactide) (PLA-b-PMPG-b-PLA)s, has been developed for the first time. PLA-b-PMPG-b-PLAs were synthesized by polycondensation of 2-methyl-1,3-propanediol and glutaric acid and successive ring-opening polymerization of L-lactide, where PMPG is an amorphous central block with low glass transition temperature and PLA is hard semicrystalline terminal blocks. The copolymers showed glass transition temperature at lower than −40 °C and melting temperature at 130–152 °C. The tensile tests of these copolymers were also performed to evaluate their mechanical properties. The degradation of the copolymers and PMPG by enzymes proteinase K and lipase PS were investigated. Microbial biodegradation in seawater was also performed at 27 °C. The triblock copolymers and PMPG homopolymer were found to show 9–15% biodegradation within 28 days, representing their relatively high biodegradability in seawater. The macromolecular structure of the triblock copolymers of PLA and PMPG can be controlled to tune their mechanical and biodegradation properties, demonstrating their potential use in various applications.
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spelling pubmed-78281332021-01-25 Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide Zahir, Lamya Kida, Takumitsu Tanaka, Ryo Nakayama, Yuushou Shiono, Takeshi Kawasaki, Norioki Yamano, Naoko Nakayama, Atsuyoshi Life (Basel) Article An innovative type of biodegradable thermoplastic elastomers with improved mechanical properties from very common and potentially renewable sources, poly(L-lactide)-b-poly(2-methyl-1,3-propylene glutarate)-b-poly(L-lactide) (PLA-b-PMPG-b-PLA)s, has been developed for the first time. PLA-b-PMPG-b-PLAs were synthesized by polycondensation of 2-methyl-1,3-propanediol and glutaric acid and successive ring-opening polymerization of L-lactide, where PMPG is an amorphous central block with low glass transition temperature and PLA is hard semicrystalline terminal blocks. The copolymers showed glass transition temperature at lower than −40 °C and melting temperature at 130–152 °C. The tensile tests of these copolymers were also performed to evaluate their mechanical properties. The degradation of the copolymers and PMPG by enzymes proteinase K and lipase PS were investigated. Microbial biodegradation in seawater was also performed at 27 °C. The triblock copolymers and PMPG homopolymer were found to show 9–15% biodegradation within 28 days, representing their relatively high biodegradability in seawater. The macromolecular structure of the triblock copolymers of PLA and PMPG can be controlled to tune their mechanical and biodegradation properties, demonstrating their potential use in various applications. MDPI 2021-01-12 /pmc/articles/PMC7828133/ /pubmed/33445658 http://dx.doi.org/10.3390/life11010043 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zahir, Lamya
Kida, Takumitsu
Tanaka, Ryo
Nakayama, Yuushou
Shiono, Takeshi
Kawasaki, Norioki
Yamano, Naoko
Nakayama, Atsuyoshi
Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide
title Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide
title_full Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide
title_fullStr Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide
title_full_unstemmed Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide
title_short Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide
title_sort synthesis, properties, and biodegradability of thermoplastic elastomers made from 2-methyl-1,3-propanediol, glutaric acid and lactide
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828133/
https://www.ncbi.nlm.nih.gov/pubmed/33445658
http://dx.doi.org/10.3390/life11010043
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