Cargando…

Characterization of SOX2, OCT4 and NANOG in Ovarian Cancer Tumor-Initiating Cells

SIMPLE SUMMARY: SOX2, OCT4, and NANOG are enriched in ovarian cancer spheroids and correlate with tumor-initiating cell markers, CD117 and ALDH/CD133. SOX2, relative to OCT4 or NANOG, is a stronger indictor of chemoresistance, tumor-initiation, and recurrent disease. Including SOX2 in evaluation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Robinson, Mikella, Gilbert, Samuel F., Waters, Jennifer A., Lujano-Olazaba, Omar, Lara, Jacqueline, Alexander, Logan J., Green, Samuel E., Burkeen, Gregory A., Patrus, Omid, Sarwar, Zinia, Holmberg, Ryne, Wang, Christine, House, Carrie D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828139/ https://www.ncbi.nlm.nih.gov/pubmed/33445692 http://dx.doi.org/10.3390/cancers13020262

Ejemplares similares

TWEAK–Fn14–RelB Signaling Cascade Promotes Stem Cell–like Features that Contribute to Post-Chemotherapy Ovarian Cancer Relapse
por: Holmberg, Ryne, et al.
Publicado: (2023)

Immunoexpression of stem cell markers SOX-2, NANOG AND OCT4 in ameloblastoma
por: Martins Balbinot, Karolyny, et al.
Publicado: (2023)

SUMOylation Represses Nanog Expression via Modulating Transcription Factors Oct4 and Sox2
por: Wu, Yongyan, et al.
Publicado: (2012)

SOX2, OCT4 and NANOG: The core embryonic stem cell pluripotency regulators in oral carcinogenesis
por: Swain, Niharika, et al.
Publicado: (2020)

Prognostic Significance of the Pluripotency Factors NANOG, SOX2, and OCT4 in Head and Neck Squamous Cell Carcinomas
por: Pedregal-Mallo, Daniel, et al.
Publicado: (2020)

The effects of embryo splitting on Cdx2, Sox2, Oct4, and Nanog gene expression in mouse blastocysts
por: Rahbaran, M., et al.
Publicado: (2022)

Expression of early transcription factors Oct-4, Sox-2 and Nanog by porcine umbilical cord (PUC) matrix cells
por: Carlin, Ryan, et al.
Publicado: (2006)

Geminin Escapes Degradation in G1 of Mouse Pluripotent Cells and Mediates the Expression of Oct4, Sox2, and Nanog
por: Yang, Valerie S., et al.
Publicado: (2011)

Insulin-like growth factor binding protein 5: Diverse roles in cancer
por: Waters, Jennifer A., et al.
Publicado: (2022)

Embryonic Stem Cells Markers SOX2, OCT4 and Nanog Expression and Their Correlations with Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma
por: Luo, Weiren, et al.
Publicado: (2013)

Enrichment of the embryonic stem cell reprogramming factors Oct4, Nanog, Myc, and Sox2 in benign and malignant vascular tumors
por: Amaya, Clarissa N., et al.
Publicado: (2015)

Expression of SOX2, NANOG and OCT4 in a mouse model of lipopolysaccharide-induced acute uterine injury and intrauterine adhesions
por: Xiao, Li, et al.
Publicado: (2017)

Relative Expression of OCT4, SOX2 and NANOG in Oral Squamous Cell Carcinoma Versus Adjacent Non- Tumor Tissue
por: Baghai Naini, Fereshteh, et al.
Publicado: (2019)

Correction: Embryonic Stem Cells Markers SOX2, OCT4 and Nanog Expression and Their Correlations with Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma
por: Luo, Weiren, et al.
Publicado: (2013)

The prognostic value of whole blood SOX2, NANOG and OCT4 mRNA expression in advanced small-cell lung cancer
por: Sodja, Eva, et al.
Publicado: (2016)

Correlation of Cancer Stem-Cell Markers OCT4, SOX2, and NANOG with Clinicopathological Features and Prognosis in Operative Patients with Rectal Cancer
por: You, Liuping, et al.
Publicado: (2018)

Nanog, Oct4 and Tet1 interplay in establishing pluripotency
por: Olariu, Victor, et al.
Publicado: (2016)

SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate
por: Kallas, Ade, et al.
Publicado: (2014)

Bright/Arid3A Acts as a Barrier to Somatic Cell Reprogramming through Direct Regulation of Oct4, Sox2, and Nanog
por: Popowski, Melissa, et al.
Publicado: (2014)

Identification and characterisation of NANOG+/ OCT-4(high)/SOX2+ doxorubicin-resistant stem-like cells from transformed trophoblastic cell lines
por: Balahmar, Reham M., et al.
Publicado: (2018)

Evaluation of the Effect of Orlistatorlistat on Expression of OCT4, Nanog, SOX2, and KLF4 Genes in Colorectal Cancer SW40 Cell Line
por: Noroozi Karimabad, Mojgan, et al.
Publicado: (2021)

293FT cells transduced with four transcription factors (OCT4, SOX2, NANOG, and LIN28) generate aberrant ES-like cells
por: Oka, Y, et al.
Publicado: (2010)

Changes in the methylation status of the Oct3/4, Nanog, and Sox2 promoters in stem cells during regeneration of rat tracheal epithelium after injury
por: Zhou, Ying, et al.
Publicado: (2016)

Structural mechanism of DNA-mediated Nanog–Sox2 cooperative interaction
por: Yesudhas, Dhanusha, et al.
Publicado: (2019)

HIF-2α Regulates NANOG Expression in Human Embryonic Stem Cells following Hypoxia and Reoxygenation through the Interaction with an Oct-Sox Cis Regulatory Element
por: Petruzzelli, Raffaella, et al.
Publicado: (2014)

Tpt1 Activates Transcription of oct4 and nanog in Transplanted Somatic Nuclei
por: Koziol, Magdalena J., et al.
Publicado: (2007)

Increased Levels of Circulating and Tissue mRNAs of Oct-4, Sox-2, Bmi-1 and Nanog is ESCC Patients: Potential Tool for Minimally Invasive Cancer Diagnosis
por: Bahl, Kriti, et al.
Publicado: (2012)

Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination
por: Johansson, Helena, et al.
Publicado: (2010)

Assessment of the Potential of CDK2 Inhibitor NU6140 to Influence the Expression of Pluripotency Markers NANOG, OCT4, and SOX2 in 2102Ep and H9 Cells
por: Kallas, Ade, et al.
Publicado: (2014)

OCT4, SOX2, and NANOG positive expression correlates with poor differentiation, advanced disease stages, and worse overall survival in HER2(+) breast cancer patients
por: Yang, Fan, et al.
Publicado: (2018)

Increased expression of stemness genes REX-1, OCT-4, NANOG, and SOX-2 in women with ovarian endometriosis versus normal endometrium: A case-control study
por: Shariati, Fatameh, et al.
Publicado: (2019)

Culture of leukocyte-derived cells from human peripheral blood: Increased expression of pluripotent genes OCT4, NANOG, SOX2, self-renewal gene TERT and plasticity
por: Lee, Yi-Jen, et al.
Publicado: (2023)

Autochthonous Mouse Melanoma and Mammary Tumors do not Express the Pluripotency Genes Oct4 and Nanog
por: Schreiber, Caroline, et al.
Publicado: (2013)

Two-stage induced differentiation of OCT4(+)/Nanog(+) stem-like cells in lung adenocarcinoma
por: Li, Rong, et al.
Publicado: (2016)

Nanog, Stat-3, and Sox-5 involvement in human fetal temporomandibular joint late development
por: Pagni, Tacia Catharine, et al.
Publicado: (2023)

Reduced Oct4 Expression Directs a Robust Pluripotent State with Distinct Signaling Activity and Increased Enhancer Occupancy by Oct4 and Nanog
por: Karwacki-Neisius, Violetta, et al.
Publicado: (2013)

Nocodazole Treatment Decreases Expression of Pluripotency Markers Nanog and Oct4 in Human Embryonic Stem Cells
por: Kallas, Ade, et al.
Publicado: (2011)

An Oct4-Sall4-Nanog network controls developmental progression in the pre-implantation mouse embryo
por: Tan, Meng How, et al.
Publicado: (2013)

The Core Stem Genes SOX2, POU5F1/OCT4, and NANOG Are Expressed in Human Parathyroid Tumors and Modulated by MEN1, YAP1, and β-catenin Pathways Activation
por: Verdelli, Chiara, et al.
Publicado: (2021)

Concurrent Expression of Oct4 and Nanog Maintains Mesenchymal Stem-Like Property of Human Dental Pulp Cells
por: Huang, Chuan-En, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_mivarpjdbfen6fmqpscu7mlfhl