Cargando…

Visceral Adipose Tissue of Prediabetic and Diabetic Females Shares a Set of Similarly Upregulated microRNAs Functionally Annotated to Inflammation, Oxidative Stress and Insulin Signaling

Hypertrophic and hypoxic visceral adipose tissue (VAT) secretes proinflammatory cytokines promoting insulin resistance (IR), prediabetes and type 2 diabetes (T2DM) microRNAs (miRNAs) are markers of metabolic disorders regulating genes critical for e.g., inflammation, glucose metabolism, and antioxid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Strycharz, Justyna, Wróblewski, Adam, Zieleniak, Andrzej, Świderska, Ewa, Matyjas, Tomasz, Rucińska, Monika, Pomorski, Lech, Czarny, Piotr, Szemraj, Janusz, Drzewoski, Józef, Śliwińska, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828194/ https://www.ncbi.nlm.nih.gov/pubmed/33445738 http://dx.doi.org/10.3390/antiox10010101

Ejemplares similares

Dysregulation of Inflammation, Oxidative Stress, and Glucose Metabolism-Related Genes and miRNAs in Visceral Adipose Tissue of Women with Type 2 Diabetes Mellitus
por: Wróblewski, Adam, et al.
Publicado: (2023)

Chronic and Intermittent Hyperglycemia Modulates Expression of Key Molecules of PI3K/AKT Pathway in Differentiating Human Visceral Adipocytes
por: Świderska, Ewa, et al.
Publicado: (2021)

Chronic and Transient Hyperglycemia Induces Changes in the Expression Patterns of IL6 and ADIPOQ Genes and Their Associated Epigenetic Modifications in Differentiating Human Visceral Adipocytes
por: Wróblewski, Adam, et al.
Publicado: (2021)

Hyperglycemia Affects miRNAs Expression Pattern during Adipogenesis of Human Visceral Adipocytes—Is Memorization Involved?
por: Strycharz, Justyna, et al.
Publicado: (2018)

Molecular Insight into the Interaction between Epigenetics and Leptin in Metabolic Disorders
por: Wróblewski, Adam, et al.
Publicado: (2019)

Hyperglycemia Changes Expression of Key Adipogenesis Markers (C/EBPα and PPARᵞ)and Morphology of Differentiating Human Visceral Adipocytes
por: Świderska, Ewa, et al.
Publicado: (2019)

Is p53 Involved in Tissue-Specific Insulin Resistance Formation?
por: Strycharz, Justyna, et al.
Publicado: (2017)

Erratum to “Is p53 Involved in Tissue-Specific Insulin Resistance Formation?”
por: Strycharz, Justyna, et al.
Publicado: (2017)

The Role of microRNAs in Metabolic Syndrome-Related Oxidative Stress
por: Włodarski, Adam, et al.
Publicado: (2020)

Metformin Induces Apoptosis in Human Pancreatic Cancer (PC) Cells Accompanied by Changes in the Levels of Histone Acetyltransferases (Particularly, p300/CBP-Associated Factor (PCAF) Protein Levels)
por: Szymczak-Pajor, Izabela, et al.
Publicado: (2023)

Single-nucleotide polymorphisms of uracil-processing genes affect the occurrence and the onset of recurrent depressive disorder
por: Czarny, Piotr, et al.
Publicado: (2018)

MicroRNA profile and iron-related gene expression in hepatitis C-related hepatocellular carcinoma: a preliminary study
por: Krupa, Renata, et al.
Publicado: (2019)

Irisin Is Related to Non-Alcoholic Fatty Liver Disease (NAFLD)
por: Kosmalski, Marcin, et al.
Publicado: (2022)

Non-Alcoholic Fatty Liver Disease or Type 2 Diabetes Mellitus—The Chicken or the Egg Dilemma
por: Kosmalski, Marcin, et al.
Publicado: (2023)

Epigenetic modifications in adipose tissue – relation to obesity and diabetes
por: Kasinska, Marta A., et al.
Publicado: (2015)

MicroRNAs and metabolic disorders – where are we heading?
por: Sliwinska, Agnieszka, et al.
Publicado: (2017)

The Molecular Mechanisms by Which Vitamin D Prevents Insulin Resistance and Associated Disorders
por: Szymczak-Pajor, Izabela, et al.
Publicado: (2020)

The Phenotype of Elderly Patients with Type 2 Diabetes Mellitus and Poor Sleep Quality
por: Mikołajczyk-Solińska, Melania, et al.
Publicado: (2020)

Non-Alcoholic Fatty Liver Disease Is Associated with a Decreased Catalase (CAT) Level, CT Genotypes and the T Allele of the -262 C/T CAT Polymorphism
por: Kosmalski, Marcin, et al.
Publicado: (2023)

Vitamin D Supplementation Reduces Both Oxidative DNA Damage and Insulin Resistance in the Elderly with Metabolic Disorders
por: Wenclewska, Sylwia, et al.
Publicado: (2019)

Impact of Single Nucleotide Polymorphisms of Base Excision Repair Genes on DNA Damage and Efficiency of DNA Repair in Recurrent Depression Disorder
por: Czarny, Piotr, et al.
Publicado: (2016)

Expression and Activity of Metalloproteinases in Depression
por: Bobińska, Kinga, et al.
Publicado: (2016)

The Importance of Epigenetics in Diagnostics and Treatment of Major Depressive Disorder
por: Czarny, Piotr, et al.
Publicado: (2021)

Single-Nucleotide Polymorphisms in Base-Excision Repair-Related Genes Involved in the Risk of an Occurrence of Non-Alcoholic Fatty Liver Disease
por: Ziółkowska, Sylwia, et al.
Publicado: (2023)

Gliclazide may have an antiapoptotic effect related to its antioxidant properties in human normal and cancer cells
por: Sliwinska, Agnieszka, et al.
Publicado: (2011)

The Interplay between Insulin Resistance, Inflammation, Oxidative Stress, Base Excision Repair and Metabolic Syndrome in Nonalcoholic Fatty Liver Disease
por: Ziolkowska, Sylwia, et al.
Publicado: (2021)

The Coexistence of Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus
por: Kosmalski, Marcin, et al.
Publicado: (2022)

The value of bacterial metagenomic analysis in post-surgical examination of gallstones
por: Ploszaj, T., et al.
Publicado: (2021)

Evaluation of oxidative stress markers in pathogenesis of diabetic neuropathy
por: Kasznicki, Jacek, et al.
Publicado: (2012)

Tumour protein 53 is linked with type 2 diabetes mellitus
por: Sliwinska, Agnieszka, et al.
Publicado: (2017)

Heart failure in the diabetic population – pathophysiology, diagnosis and management
por: Kasznicki, Jacek, et al.
Publicado: (2014)

The Current and Potential Therapeutic Use of Metformin—The Good Old Drug
por: Drzewoski, Józef, et al.
Publicado: (2021)

Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation
por: Cichoń, Natalia, et al.
Publicado: (2017)

Novel association between TGFA, TGFB1, IRF1, PTGS2 and IKBKB single-nucleotide polymorphisms and occurrence, severity and treatment response of major depressive disorder
por: Bialek, Katarzyna, et al.
Publicado: (2020)

Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome
por: Kusaka, Hiroaki, et al.
Publicado: (2016)

Association between visceral adiposity index and risk of prediabetes: A meta‐analysis of observational studies
por: Wang, Dan, et al.
Publicado: (2021)

Measurement of visceral fat for early prediction of prediabetes—Cross-sectional study from Southern India
por: Jadhav, Radhika A., et al.
Publicado: (2022)

Plasma Lipid Profiling Shows Similar Associations with Prediabetes and Type 2 Diabetes
por: Meikle, Peter J., et al.
Publicado: (2013)

Determining similarity of scientific entities in annotation datasets
por: Palma, Guillermo, et al.
Publicado: (2015)

Improving automatic GO annotation with semantic similarity
por: Sarker, Bishnu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r92svksvehhg2l1dim0conrbs0