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Elevated Expression of Cathepsin K in Periodontal Ligament Fibroblast by Inflammatory Cytokines Accelerates Osteoclastogenesis via Paracrine Mechanism in Periodontal Disease

Cathepsin K (CTSK) is a cysteine protease that is mainly produced from mature osteoclasts and contributes to the destruction of connective tissues and mineralized matrix as a consequence of periodontal disease (PD). However, few studies have reported its regulatory role in osteoclastogenesis-support...

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Detalles Bibliográficos
Autores principales: Heo, Soon Chul, Kim, Yu Na, Choi, YunJeong, Joo, Ji-Young, Hwang, Jae Joon, Bae, Moon-Kyoung, Kim, Hyung Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828200/
https://www.ncbi.nlm.nih.gov/pubmed/33445732
http://dx.doi.org/10.3390/ijms22020695

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