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Lipocalin-2 Deficiency Reduces Oxidative Stress and Neuroinflammation and Results in Attenuation of Kainic Acid-Induced Hippocampal Cell Death
The hippocampal cell death that follows kainic acid (KA)-induced seizures is associated with blood–brain barrier (BBB) leakage and oxidative stress. Lipocalin-2 (LCN2) is an iron-trafficking protein which contributes to both oxidative stress and inflammation. However, LCN2′s role in KA-induced hippo...
Autores principales: | Shin, Hyun Joo, Jeong, Eun Ae, Lee, Jong Youl, An, Hyeong Seok, Jang, Hye Min, Ahn, Yu Jeong, Lee, Jaewoong, Kim, Kyung Eun, Roh, Gu Seob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828212/ https://www.ncbi.nlm.nih.gov/pubmed/33445746 http://dx.doi.org/10.3390/antiox10010100 |
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