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Control of Mesenchymal Stromal Cell Senescence by Tryptophan Metabolites

Cellular senescence contributes to aging and age-related disorders. High glucose (HG) induces mesenchymal stromal/stem cell (MSC) senescence, which hampers cell expansion and impairs MSC function. Intracellular HG triggers metabolic shift from aerobic glycolysis to oxidative phosphorylation, resulti...

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Detalles Bibliográficos
Autor principal:	Wu, Kenneth K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828284/ https://www.ncbi.nlm.nih.gov/pubmed/33445766 http://dx.doi.org/10.3390/ijms22020697

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