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Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL

Endothelial lipase (EL) is a strong modulator of the high-density lipoprotein (HDL) structure, composition, and function. Here, we examined the impact of EL on HDL paraoxonase 1 (PON1) content and arylesterase (AE) activity in vitro and in vivo. The incubation of HDL with EL-overexpressing HepG2 cel...

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Detalles Bibliográficos
Autores principales: Schilcher, Irene, Stadler, Julia T., Lechleitner, Margarete, Hrzenjak, Andelko, Berghold, Andrea, Pregartner, Gudrun, Lhomme, Marie, Holzer, Michael, Korbelius, Melanie, Reichmann, Florian, Springer, Anna, Wadsack, Christian, Madl, Tobias, Kratky, Dagmar, Kontush, Anatol, Marsche, Gunther, Frank, Saša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828365/
https://www.ncbi.nlm.nih.gov/pubmed/33450841
http://dx.doi.org/10.3390/ijms22020719