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In Vivo Inhibition of Marek’s Disease Virus in Transgenic Chickens Expressing Cas9 and gRNA against ICP4

Marek’s disease (MD), caused by MD herpesvirus (MDV), is an economically important disease in chickens. The efficacy of the existing vaccines against evolving virulent stains may become limited and necessitates the development of novel antiviral strategies to protect poultry from MDV strains with in...

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Detalles Bibliográficos
Autores principales:	Challagulla, Arjun, Jenkins, Kristie A., O’Neil, Terri E., Shi, Shunning, Morris, Kirsten R., Wise, Terry G., Paradkar, Prasad N., Tizard, Mark L., Doran, Timothy J., Schat, Karel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828426/ https://www.ncbi.nlm.nih.gov/pubmed/33450980 http://dx.doi.org/10.3390/microorganisms9010164

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