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Synthesis and Evaluation of Novel Iminosugars Prepared from Natural Amino Acids

Cyclopropanated iminosugars have a locked conformation that may enhance the inhibitory activity and selectivity against different glycosidases. We show the synthesis of new cyclopropane-containing piperidines bearing five stereogenic centers from natural amino acids l-serine and l-alanine. Those pre...

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Detalles Bibliográficos
Autores principales:	Puet, Alejandro, Domínguez, Gema, Cañada, Francisco Javier, Pérez-Castells, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828477/ https://www.ncbi.nlm.nih.gov/pubmed/33451060 http://dx.doi.org/10.3390/molecules26020394

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