Cargando…

AhR and Cancer: From Gene Profiling to Targeted Therapy

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been shown to be an essential regulator of a broad spectrum of biological activities required for maintaining the body’s vital functions. AhR also plays a critical role in tumorigenesis. Its role in cancer is com...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paris, Anaïs, Tardif, Nina, Galibert, Marie-Dominique, Corre, Sébastien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828536/ https://www.ncbi.nlm.nih.gov/pubmed/33451095 http://dx.doi.org/10.3390/ijms22020752

Ejemplares similares

Role of Flavonoids in the Prevention of AhR-Dependent Resistance During Treatment with BRAF Inhibitors
por: Leclair, Héloïse M., et al.
Publicado: (2020)

The AhR‐SRC axis as a therapeutic vulnerability in BRAFi‐resistant melanoma
por: Paris, Anaïs, et al.
Publicado: (2022)

Tumor-Suppressive Functions of the Aryl Hydrocarbon Receptor (AhR) and AhR as a Therapeutic Target in Cancer
por: Elson, Daniel J., et al.
Publicado: (2023)

The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions
por: Gargaro, Marco, et al.
Publicado: (2021)

Induction of AhR-Mediated Gene Transcription by Coffee
por: Ishikawa, Toshio, et al.
Publicado: (2014)

Serotonin Modulates AhR Activation by Interfering with CYP1A1-Mediated Clearance of AhR Ligands
por: Manzella, Christopher R., et al.
Publicado: (2020)

Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα
por: Ge, Luna, et al.
Publicado: (2018)

New Treatments in Renal Cancer: The AhR Ligands
por: Itkin, Boris, et al.
Publicado: (2020)

Coactivator Recruitment of AhR/ARNT1
por: Endler, Alexander, et al.
Publicado: (2014)

AhR signaling pathways and regulatory functions
por: Larigot, Lucie, et al.
Publicado: (2018)

Epigenetic Regulations of AhR in the Aspect of Immunomodulation
por: Wajda, Anna, et al.
Publicado: (2020)

AhR promotes phosphorylation of ARNT isoform 1 in human T cell malignancies as a switch for optimal AhR activity
por: Bourner, Luke A., et al.
Publicado: (2022)

AhR and IDO1 in pathogenesis of Covid-19 and the “Systemic AhR Activation Syndrome:” a translational review and therapeutic perspectives
por: Turski, Waldemar A., et al.
Publicado: (2020)

Ethyl Caffeate Can Inhibit Aryl Hydrocarbon Receptor (AhR) Signaling and AhR-Mediated Potentiation of Mast Cell Activation
por: Nguyen, Phuc-Tan, et al.
Publicado: (2023)

AhR-deficiency as a cause of demyelinating disease and inflammation
por: Juricek, Ludmila, et al.
Publicado: (2017)

Role of AhR/ARNT system in skin homeostasis
por: Furue, Masutaka, et al.
Publicado: (2014)

Bidirectional talk between AhR and Oct4
por: Kang, Bo, et al.
Publicado: (2015)

Herbal Plants: The Role of AhR in Mediating Immunomodulation
por: Bungsu, Izzah, et al.
Publicado: (2021)

Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles
por: Yang, Fang, et al.
Publicado: (2020)

Targeting AhR as a Novel Therapeutic Modality against Inflammatory Diseases
por: Cannon, Alkeiver S., et al.
Publicado: (2021)

The inhibition of lung cancer cell migration by AhR-regulated autophagy
por: Tsai, Chi-Hao, et al.
Publicado: (2017)

Environmental exposure and the role of AhR in the tumor microenvironment of breast cancer
por: Sweeney, Colleen, et al.
Publicado: (2022)

The Role of the Kynurenine/AhR Pathway in Diseases Related to Metabolism and Cancer
por: Shadboorestan, Amir, et al.
Publicado: (2023)

Role of the Arylhydrocarbon Receptor (AhR) in the Pathology of Asthma and COPD
por: Chiba, Takahito, et al.
Publicado: (2012)

The Role of Aryl Hydrocarbon Receptor (AhR) in Brain Tumors
por: Perepechaeva, Maria L., et al.
Publicado: (2020)

The Role of AhR in the Hallmarks of Brain Aging: Friend and Foe
por: Ojo, Emmanuel S., et al.
Publicado: (2021)

Molecular Docking of Natural Compounds for Potential Inhibition of AhR
por: Giordano, Deborah, et al.
Publicado: (2023)

AhR and Wnt/β-Catenin Signaling Pathways and Their Interplay
por: Grishanova, Alevtina Y., et al.
Publicado: (2023)

Gene expression profiling of the Notch-AhR-IL22 axis at homeostasis and in response to tissue injury
por: Weidenbusch, Marc, et al.
Publicado: (2017)

The Role of the Aryl Hydrocarbon Receptor (AhR) and Its Ligands in Breast Cancer
por: Safe, Stephen, et al.
Publicado: (2022)

Regulation of IDO2 by the Aryl Hydrocarbon Receptor (AhR) in Breast Cancer
por: Kado, Sarah Y., et al.
Publicado: (2023)

AhR transcriptional activity in serum of Inuits across Greenlandic districts
por: Long, Manhai, et al.
Publicado: (2007)

AhR-Mediated, Non-Genomic Modulation of IDO1 Function
por: Pallotta, Maria Teresa, et al.
Publicado: (2014)

AhR-Mediated Effects of Dioxin on Neuronal Acetylcholinesterase Expression in Vitro
por: Xie, Heidi Qunhui, et al.
Publicado: (2013)

The Coevolution of IDO1 and AhR in the Emergence of Regulatory T-Cells in Mammals
por: Grohmann, Ursula, et al.
Publicado: (2015)

The Role of Aryl-Hydrocarbon Receptor (AhR) in Osteoclast Differentiation and Function
por: Park, Robin, et al.
Publicado: (2020)

Pharmaceutically Active Microbial AhR Agonists as Innovative Biodrugs in Inflammation
por: Puccetti, Matteo, et al.
Publicado: (2022)

Developmental Origins of Delayed Adult Immune Response: The AhR Connection
por: Pascual, Florencia
Publicado: (2021)

The biological interactions between kynurenine and AhR in melanocytes: in vitro studies
por: Walczak, Katarzyna, et al.
Publicado: (2023)

AhR activation defends gut barrier integrity against damage occurring in obesity
por: Postal, Bárbara G., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2kk28006hmrvvrru8cc70dgb4a