Cargando…
A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses
Breast cancer (BC) is the most common cancer among women worldwide. More than 70% of BC cases express estrogen receptor alpha (ERα), a central transcription factor that stimulates the proliferation of breast cancer cells, usually in the presence of estrogen. While most cases of ER-positive BC initia...
Autores principales: | Clusan, Léa, Le Goff, Pascale, Flouriot, Gilles, Pakdel, Farzad |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828590/ https://www.ncbi.nlm.nih.gov/pubmed/33451133 http://dx.doi.org/10.3390/ijms22020756 |
Ejemplares similares
-
A Basic Review on Estrogen Receptor Signaling Pathways in Breast Cancer
por: Clusan, Léa, et al.
Publicado: (2023) -
Codon adaptation by synonymous mutations impacts the functional properties of the estrogen receptor‐alpha protein in breast cancer cells
por: Clusan, Léa, et al.
Publicado: (2023) -
Differential Estrogen-Regulation of CXCL12 Chemokine Receptors, CXCR4 and CXCR7, Contributes to the Growth Effect of Estrogens in Breast Cancer Cells
por: Boudot, Antoine, et al.
Publicado: (2011) -
Unliganded Estrogen Receptor Alpha Promotes PC12 Survival during Serum Starvation
por: Ferriere, François, et al.
Publicado: (2013) -
Apigenin, a Partial Antagonist of the Estrogen Receptor (ER), Inhibits ER-Positive Breast Cancer Cell Proliferation through Akt/FOXM1 Signaling
por: Pham, Thu Ha, et al.
Publicado: (2021)