Cargando…

JAK3 Is Expressed in the Nucleus of Malignant T Cells in Cutaneous T Cell Lymphoma (CTCL)

SIMPLE SUMMARY: JAK3 plays an important role in the pathogenesis of cutaneous T cell lymphoma. JAK3 belongs to the Janus kinase family of receptor-associated tyrosine kinases located in cytoplasm adjacent to the plasma membrane. In this study, we show that JAK3 can also be ectopically expressed in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vadivel, Chella Krishna, Gluud, Maria, Torres-Rusillo, Sara, Boding, Lasse, Willerslev-Olsen, Andreas, Buus, Terkild B., Nielsen, Tea Kirkegaard, Persson, Jenny L., Bonefeld, Charlotte M., Geisler, Carsten, Krejsgaard, Thorbjorn, Fuglsang, Anja T., Odum, Niels, Woetmann, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828698/ https://www.ncbi.nlm.nih.gov/pubmed/33466582 http://dx.doi.org/10.3390/cancers13020280

Ejemplares similares

Concomitant Inhibition of FASN and SREBP Provides a Promising Therapy for CTCL
por: Chi, Cheng, et al.
Publicado: (2022)

Cellular Interactions and Inflammation in the Pathogenesis of Cutaneous T-Cell Lymphoma
por: Stolearenco, Veronica, et al.
Publicado: (2020)

B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with dasatinib in cutaneous T-cell lymphoma (CTCL)
por: Petersen, D L, et al.
Publicado: (2014)

MicroRNAs in the Pathogenesis, Diagnosis, Prognosis and Targeted Treatment of Cutaneous T-Cell Lymphomas
por: Gluud, Maria, et al.
Publicado: (2020)

Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4(+) T cells in cutaneous T-cell lymphoma
por: Blümel, Edda, et al.
Publicado: (2019)

In vitro differentiated human CD4(+) T cells produce hepatocyte growth factor
por: Ford, Shayne Lavondua, et al.
Publicado: (2023)

Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome
por: Willerslev-Olsen, Andreas, et al.
Publicado: (2020)

Bacterial Toxins Fuel Disease Progression in Cutaneous T-Cell Lymphoma
por: Willerslev-Olsen, Andreas, et al.
Publicado: (2013)

MicroRNA-106b Regulates Expression of the Tumour Suppressors p21 and TXNIP and Promotes Tumour Cell Proliferation in Mycosis Fungoides
por: LINDAHL, Lise M., et al.
Publicado: (2020)

Staphylococcus aureus alpha-toxin inhibits CD8(+) T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma
por: Blümel, Edda, et al.
Publicado: (2020)

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma
por: Sibbesen, Nina A., et al.
Publicado: (2015)

Midline 1 controls polarization and migration of murine cytotoxic T cells
por: Boding, Lasse, et al.
Publicado: (2014)

Publisher Correction: Inhibition of succinate dehydrogenase activity impairs human T cell activation and function
por: Nastasi, Claudia, et al.
Publicado: (2021)

Inhibition of succinate dehydrogenase activity impairs human T cell activation and function
por: Nastasi, Claudia, et al.
Publicado: (2021)

The effect of short-chain fatty acids on human monocyte-derived dendritic cells
por: Nastasi, Claudia, et al.
Publicado: (2015)

Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin
por: Woetmann, Anders, et al.
Publicado: (2018)

Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients
por: Bagdonaite, Ieva, et al.
Publicado: (2015)

Vitamin D Up-Regulates the Vitamin D Receptor by Protecting It from Proteasomal Degradation in Human CD4(+) T Cells
por: Kongsbak, Martin, et al.
Publicado: (2014)

Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome
por: Hu, Tengpeng, et al.
Publicado: (2019)

Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus
por: Buus, Terkild Brink, et al.
Publicado: (2017)

Butyrate and propionate inhibit antigen-specific CD8(+) T cell activation by suppressing IL-12 production by antigen-presenting cells
por: Nastasi, Claudia, et al.
Publicado: (2017)

Increased Production of IL-17A-Producing γδ T Cells in the Thymus of Filaggrin-Deficient Mice
por: Jee, Mia Hamilton, et al.
Publicado: (2018)

STAT5 induces miR-21 expression in cutaneous T cell lymphoma
por: Lindahl, Lise M., et al.
Publicado: (2016)

Malignant T cells activate endothelial cells via IL-17 F
por: Lauenborg, B, et al.
Publicado: (2017)

Vitamin D Inhibits IL-22 Production Through a Repressive Vitamin D Response Element in the il22 Promoter
por: Lopez, Daniel V., et al.
Publicado: (2021)

miRNA Signature in Early-stage Mycosis Fungoides
por: SØRENSEN, Sissel T., et al.
Publicado: (2022)

Development of interleukin-17-producing Vγ2(+) γδ T cells is reduced by ICOS signaling in the thymus
por: Buus, Terkild Brink, et al.
Publicado: (2016)

Analysis of CTCL cell lines reveals important differences between mycosis fungoides/Sézary syndrome vs. HTLV-1(+) leukemic cell lines
por: Netchiporouk, Elena, et al.
Publicado: (2017)

Impaired Vitamin D Signaling in T Cells From a Family With Hereditary Vitamin D Resistant Rickets
por: Al-Jaberi, Fatima A. H., et al.
Publicado: (2021)

Malignant inflammation in cutaneous T‐cell lymphoma—a hostile takeover
por: Krejsgaard, Thorbjørn, et al.
Publicado: (2016)

Human CD4(+) T cells require exogenous cystine for glutathione and DNA synthesis
por: Levring, Trine B., et al.
Publicado: (2015)

Investigating heredity in cutaneous T-cell lymphoma in a unique cohort of Danish twins
por: Odum, N, et al.
Publicado: (2017)

Vitamin D-binding protein controls T cell responses to vitamin D
por: Kongsbak, Martin, et al.
Publicado: (2014)

Macrophages Control the Bioavailability of Vitamin D and Vitamin D-Regulated T Cell Responses
por: Lopez, Daniel Villalba, et al.
Publicado: (2021)

Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor
por: Rode, Anna K. O., et al.
Publicado: (2022)

Brentuximab vedotin: targeting CD30 as standard in CTCL
por: Prince, H. Miles, et al.
Publicado: (2018)

Simultaneous Inhibition of mTOR-Containing Complex 1 (mTORC1) and MNK Induces Apoptosis of Cutaneous T-Cell Lymphoma (CTCL) Cells
por: Marzec, Michal, et al.
Publicado: (2011)

Normal T and B Cell Responses Against SARS-CoV-2 in a Family With a Non-Functional Vitamin D Receptor: A Case Report
por: Kongsbak-Wismann, Martin, et al.
Publicado: (2021)

Update on the treatment of cutaneous T-cell lymphoma (CTCL): Focus on vorinostat
por: Duvic, Madeleine, et al.
Publicado: (2007)

Activated human CD4(+) T cells express transporters for both cysteine and cystine
por: Levring, Trine Bøegh, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_5oe3drhf23vlr0ggt238qhln2m