Cargando…

The Neosartorya fischeri Antifungal Protein 2 (NFAP2): A New Potential Weapon against Multidrug-Resistant Candida auris Biofilms

Candida auris is a potential multidrug-resistant pathogen able to persist on indwelling devices as a biofilm, which serve as a source of catheter-associated infections. Neosartorya fischeri antifungal protein 2 (NFAP2) is a cysteine-rich, cationic protein with potent anti-Candida activity. We studie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kovács, Renátó, Nagy, Fruzsina, Tóth, Zoltán, Forgács, Lajos, Tóth, Liliána, Váradi, Györgyi, Tóth, Gábor K., Vadászi, Karina, Borman, Andrew M., Majoros, László, Galgóczy, László
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828714/ https://www.ncbi.nlm.nih.gov/pubmed/33466640 http://dx.doi.org/10.3390/ijms22020771

Ejemplares similares

Biofungicidal Potential of Neosartorya (Aspergillus) Fischeri Antifungal Protein NFAP and Novel Synthetic γ-Core Peptides
por: Tóth, Liliána, et al.
Publicado: (2020)

Structural determinants of Neosartorya fischeri antifungal protein (NFAP) for folding, stability and antifungal activity
por: Galgóczy, László, et al.
Publicado: (2017)

Anti-Candidal Activity and Functional Mapping of Recombinant and Synthetic Neosartorya fischeri Antifungal Protein 2 (NFAP2)
por: Tóth, Liliána, et al.
Publicado: (2018)

NFAP2, a novel cysteine-rich anti-yeast protein from Neosartorya fischeri NRRL 181: isolation and characterization
por: Tóth, Liliána, et al.
Publicado: (2016)

Insight into the antifungal mechanism of Neosartorya fischeri antifungal protein
por: Virágh, Máté, et al.
Publicado: (2015)

Hard nut to crack: Solving the disulfide linkage pattern of the Neosartorya (Aspergillus) fischeri antifungal protein 2
por: Váradi, Györgyi, et al.
Publicado: (2023)

The combination of Neosartorya (Aspergillus) fischeri antifungal proteins with rationally designed γ-core peptide derivatives is effective for plant and crop protection
por: Tóth, Liliána, et al.
Publicado: (2022)

In vitro and in vivo Effect of Exogenous Farnesol Exposure Against Candida auris
por: Nagy, Fruzsina, et al.
Publicado: (2020)

Comparison of In Vitro Killing Activity of Rezafungin, Anidulafungin, Caspofungin, and Micafungin against Four Candida auris Clades in RPMI-1640 in the Absence and Presence of Human Serum
por: Kovács, Renátó, et al.
Publicado: (2021)

Comparison of in vivo pathogenicity of four Candida auris clades in a neutropenic bloodstream infection murine model
por: Forgács, Lajos, et al.
Publicado: (2020)

Total transcriptome analysis of Candida auris planktonic cells exposed to tyrosol
por: Balla, Noémi, et al.
Publicado: (2023)

In Vivo Efficacy of Amphotericin B against Four Candida auris Clades
por: Forgács, Lajos, et al.
Publicado: (2022)

Transcriptional Profiling of the Candida auris Response to Exogenous Farnesol Exposure
por: Jakab, Ágnes, et al.
Publicado: (2021)

In Vitro Killing Activities of Anidulafungin and Micafungin with and without Nikkomycin Z against Four Candida auris Clades
por: Adnan, Awid, et al.
Publicado: (2023)

Unpredictable In Vitro Killing Activity of Amphotericin B against Four Candida auris Clades
por: Papp, Zoltán, et al.
Publicado: (2021)

In vitro activity of rezafungin against common and rare Candida species and Saccharomyces cerevisiae
por: Tóth, Zoltán, et al.
Publicado: (2019)

Relative Frequency of Paradoxical Growth and Trailing Effect with Caspofungin, Micafungin, Anidulafungin, and the Novel Echinocandin Rezafungin against Candida Species
por: Tóth, Zoltán, et al.
Publicado: (2020)

Rationally Designed Antimicrobial Peptides Are Potential Tools to Combat Devastating Bacteria and Fungi
por: Váradi, Györgyi, et al.
Publicado: (2022)

Synergistic Interaction of Caspofungin Combined with Posaconazole against FKS Wild-Type and Mutant Candida auris Planktonic Cells and Biofilms
por: Balla, Noémi, et al.
Publicado: (2022)

Efficacy of humanized single large doses of caspofungin on the lethality and fungal tissue burden in a deeply neutropenic murine model against Candida albicans and Candida dubliniensis
por: Prépost, Eszter, et al.
Publicado: (2019)

Solution Structure, Dynamics, and New Antifungal Aspects of the Cysteine-Rich Miniprotein PAFC
por: Czajlik, András, et al.
Publicado: (2021)

The potential use of the Penicillium chrysogenum antifungal protein PAF, the designed variant PAF(opt) and its γ‐core peptide Pγ(opt) in plant protection
por: Tóth, Liliána, et al.
Publicado: (2020)

The Evolutionary Conserved γ-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF
por: Sonderegger, Christoph, et al.
Publicado: (2018)

The In Vitro Activity of Fluconazole, Amphotericin B and Echinocandins Against Cyberlindnera fabianii Planktonic Cells and Biofilms
por: Tóth, Zoltán, et al.
Publicado: (2022)

The Role of Uniform Meropenem Usage in Acinetobacter baumannii Clone Replacement
por: Balázs, Bence, et al.
Publicado: (2021)

First evidence of mineralization of petroleum asphaltenes by a strain of Neosartorya fischeri
por: Uribe‐Alvarez, Cristina, et al.
Publicado: (2011)

Confirmation of the Disulfide Connectivity and Strategies for Chemical Synthesis of the Four-Disulfide-Bond-Stabilized Aspergillus giganteus Antifungal Protein, AFP
por: Váradi, Györgyi, et al.
Publicado: (2023)

Functionality and prevalence of trehalose-based oligosaccharides as novel compatible solutes in ascospores of Neosartorya fischeri (Aspergillus fischeri) and other fungi
por: Wyatt, Timon T, et al.
Publicado: (2015)

Structure and Synthesis of Antifungal Disulfide β-Strand Proteins from Filamentous Fungi
por: Váradi, Györgyi, et al.
Publicado: (2018)

Antifungal Activity of an Original Amino-Isocyanonaphthalene (ICAN) Compound Family: Promising Broad Spectrum Antifungals
por: Nagy, Miklós, et al.
Publicado: (2020)

Studies on the Chemical Diversities of Secondary Metabolites Produced by Neosartorya fischeri via the OSMAC Method
por: Ying, You-Min, et al.
Publicado: (2018)

Microarray analysis of Neosartorya fischeri using different carbon sources, petroleum asphaltenes and glucose-peptone
por: Hernández-López, Edna L., et al.
Publicado: (2015)

The Penicillium chrysogenum Q176 Antimicrobial Protein PAFC Effectively Inhibits the Growth of the Opportunistic Human Pathogen Candida albicans
por: Holzknecht, Jeanett, et al.
Publicado: (2020)

Faecal Carriage of Carbapenem-Resistant Acinetobacter baumannii: Comparison to Clinical Isolates from the Same Period (2017–2019)
por: Balázs, Bence, et al.
Publicado: (2022)

Fungal Quorum-Sensing Molecules: A Review of Their Antifungal Effect against Candida Biofilms
por: Kovács, Renátó, et al.
Publicado: (2020)

Synthesis of isobemisiose, neosartose, and fischerose: three α-1,6-linked trehalose-based oligosaccharides identified from Neosartorya fischeri
por: Kuenstner, E. J., et al.
Publicado: (2020)

Comparison of Chemical Sensitivity of Fresh and Long-Stored Heat Resistant Neosartorya fischeri Environmental Isolates Using BIOLOG Phenotype MicroArray System
por: Panek, Jacek, et al.
Publicado: (2016)

Do Antimicrobial Proteins Contribute to Overcoming the Hidden Antifungal Crisis at the Dawn of a Post-Antibiotic Era?
por: Galgóczy, László, et al.
Publicado: (2019)

Molecular Characterization of a Highly-Active Thermophilic β-Glucosidase from Neosartorya fischeri P1 and Its Application in the Hydrolysis of Soybean Isoflavone Glycosides
por: Yang, Xinzhuo, et al.
Publicado: (2014)

Heme Oxygenase-1 (HMX1) Loss of Function Increases the In-Host Fitness of the Saccharomyces ‘boulardii’ Probiotic Yeast in a Mouse Fungemia Model
por: Imre, Alexandra, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jdafv5d06vrp02q2funqefolnr