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In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism
Introduction: The aim of this study was to evaluate the in-hospital and short-term predictive factors of mortality in intermediate-high risk acute pulmonary embolism (PE) patients with right ventricle (RV)dysfunction and myocardial injury. Methods: In this retrospective study, the medical records of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828758/ https://www.ncbi.nlm.nih.gov/pubmed/33510882 http://dx.doi.org/10.34172/jcvtr.2020.51 |
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author | Gök, Gulay Karadağ, Mehmet Çinar, Tufan Nurkalem, Zekeriya Duman, Dursun |
author_facet | Gök, Gulay Karadağ, Mehmet Çinar, Tufan Nurkalem, Zekeriya Duman, Dursun |
author_sort | Gök, Gulay |
collection | PubMed |
description | Introduction: The aim of this study was to evaluate the in-hospital and short-term predictive factors of mortality in intermediate-high risk acute pulmonary embolism (PE) patients with right ventricle (RV)dysfunction and myocardial injury. Methods: In this retrospective study, the medical records of 187 patients with a diagnosis of intermediate high risk acute PE were evaluated. A contrast-enhanced multi-detector pulmonary angiography was used to confirm diagnosis in all cases. All-cause mortality was determined by obtaining both in hospital and 30 days follow-up data of patients from medical records. Results: During the in-hospital stay (9.5±4.72 days), 7 patients died, resulting in an acute PE related in-hospital mortality of 3.2%. Admission heart rate (HR), (Odds ratio (OR), 1.028 95% Confidence interval (CI), 0.002-1.121; P = 0.048) and blood urea nitrogen (BUN) (OR, 1.028 95% CI, 0.002-1.016; P = 0.044) were found to be independent predictors for in-hospital mortality in a multi variate logistic regression analysis. In total, 32 patients (20.9%) died during 30 days follow-up.The presence of congestive heart failure (OR, 0.015, 95%CI, 0.001-0.211; P = 0.002) and dementia (OR, 0.029, 95%CI,0.002-0.516; P = 0.016) as well as low albumin level (OR, 0.049 95%CI, 0.006-0.383; P = 0.049) were associated with 30 days mortality. Conclusion: HR and BUN were independent predictors of in-hospital mortality and the presence of congestive heart failure, dementia, and low albumin levels were associated with higher 30 days mortality. |
format | Online Article Text |
id | pubmed-7828758 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Tabriz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-78287582021-01-27 In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism Gök, Gulay Karadağ, Mehmet Çinar, Tufan Nurkalem, Zekeriya Duman, Dursun J Cardiovasc Thorac Res Original Article Introduction: The aim of this study was to evaluate the in-hospital and short-term predictive factors of mortality in intermediate-high risk acute pulmonary embolism (PE) patients with right ventricle (RV)dysfunction and myocardial injury. Methods: In this retrospective study, the medical records of 187 patients with a diagnosis of intermediate high risk acute PE were evaluated. A contrast-enhanced multi-detector pulmonary angiography was used to confirm diagnosis in all cases. All-cause mortality was determined by obtaining both in hospital and 30 days follow-up data of patients from medical records. Results: During the in-hospital stay (9.5±4.72 days), 7 patients died, resulting in an acute PE related in-hospital mortality of 3.2%. Admission heart rate (HR), (Odds ratio (OR), 1.028 95% Confidence interval (CI), 0.002-1.121; P = 0.048) and blood urea nitrogen (BUN) (OR, 1.028 95% CI, 0.002-1.016; P = 0.044) were found to be independent predictors for in-hospital mortality in a multi variate logistic regression analysis. In total, 32 patients (20.9%) died during 30 days follow-up.The presence of congestive heart failure (OR, 0.015, 95%CI, 0.001-0.211; P = 0.002) and dementia (OR, 0.029, 95%CI,0.002-0.516; P = 0.016) as well as low albumin level (OR, 0.049 95%CI, 0.006-0.383; P = 0.049) were associated with 30 days mortality. Conclusion: HR and BUN were independent predictors of in-hospital mortality and the presence of congestive heart failure, dementia, and low albumin levels were associated with higher 30 days mortality. Tabriz University of Medical Sciences 2020 2020-11-28 /pmc/articles/PMC7828758/ /pubmed/33510882 http://dx.doi.org/10.34172/jcvtr.2020.51 Text en © 2020 The Author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Gök, Gulay Karadağ, Mehmet Çinar, Tufan Nurkalem, Zekeriya Duman, Dursun In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism |
title | In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism |
title_full | In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism |
title_fullStr | In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism |
title_full_unstemmed | In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism |
title_short | In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism |
title_sort | in-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828758/ https://www.ncbi.nlm.nih.gov/pubmed/33510882 http://dx.doi.org/10.34172/jcvtr.2020.51 |
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