Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H(2)O(2) Together with Bicarbonate

Protein tyrosine phosphatases (PTPs) can be regulated by several redox-dependent mechanisms and control growth factor-activated receptor tyrosine kinase phosphorylation cascades. Reversible oxidation of PTPs is counteracted by reductive enzymes, including thioredoxin (Trx) and Trx-related protein of...

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Detalles Bibliográficos
Autores principales: Dagnell, Markus, Cheng, Qing, Arnér, Elias S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828775/
https://www.ncbi.nlm.nih.gov/pubmed/33466723
http://dx.doi.org/10.3390/antiox10010111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828775/
https://www.ncbi.nlm.nih.gov/pubmed/33466723
http://dx.doi.org/10.3390/antiox10010111

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