Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis in the Human Hepatoma Cell Line HepaRG

1,2-unsaturated pyrrolizidine alkaloids (PAs) belong to a group of secondary plant metabolites. Exposure to PA-contaminated feed and food may cause severe hepatotoxicity. A pathway possibly involved in PA toxicity is the disturbance of bile acid homeostasis. Therefore, in this study, the influence o...

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Detalles Bibliográficos
Autores principales: Waizenegger, Julia, Glück, Josephin, Henricsson, Marcus, Luckert, Claudia, Braeuning, Albert, Hessel-Pras, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828834/
https://www.ncbi.nlm.nih.gov/pubmed/33466663
http://dx.doi.org/10.3390/foods10010161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828834/
https://www.ncbi.nlm.nih.gov/pubmed/33466663
http://dx.doi.org/10.3390/foods10010161

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