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Binding of alpha-ACTN4 to EGF receptor enables its rapid phosphorylation

Alpha-ACTN4, a member of alpha-actinin family is critical for cell motility through its regulated binding of actin filaments. We previously found that EGF exposure of cells triggers the tyrosyl-phosphorylation of ACTN4 in fibroblasts that dramatically downregulates its binding to actin filaments. Ho...

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Detalles Bibliográficos
Autores principales: Shao, Hanshuang, Wells, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829150/
https://www.ncbi.nlm.nih.gov/pubmed/33532643
http://dx.doi.org/10.1016/j.heliyon.2021.e06011