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Binding of alpha-ACTN4 to EGF receptor enables its rapid phosphorylation
Alpha-ACTN4, a member of alpha-actinin family is critical for cell motility through its regulated binding of actin filaments. We previously found that EGF exposure of cells triggers the tyrosyl-phosphorylation of ACTN4 in fibroblasts that dramatically downregulates its binding to actin filaments. Ho...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829150/ https://www.ncbi.nlm.nih.gov/pubmed/33532643 http://dx.doi.org/10.1016/j.heliyon.2021.e06011 |