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In Vitro Tests for Assessing the Neutralizing Ability of Snake Antivenoms: Toward the 3Rs Principles

There is an urgent need to strengthen the implementation of the 3Rs principle (Replacement, Reduction and Refinement) in the use of experimental animals in toxinological research and in the assessment of the neutralizing efficacy of snake antivenoms. This is a challenging task owing to the inherent...

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Detalles Bibliográficos
Autores principales: Gutiérrez, José María, Vargas, Mariángela, Segura, Álvaro, Herrera, María, Villalta, Mauren, Solano, Gabriela, Sánchez, Andrés, Herrera, Cristina, León, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829219/
https://www.ncbi.nlm.nih.gov/pubmed/33505403
http://dx.doi.org/10.3389/fimmu.2020.617429