Cargando…

The Use of Vitamin K2 in Patients With Parkinson's Disease and Mitochondrial Dysfunction (PD-K2): A Theranostic Pilot Study in a Placebo-Controlled Parallel Group Design

Background: Despite rapid advances in research on Parkinson's disease (PD), in particular in the elucidation of genetic contributions, no disease-modifying therapy has become available to date. Objectives: In the proposed project, we aim to investigate the potential effects of vitamin K2 (long-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prasuhn, Jannik, Kasten, Meike, Vos, Melissa, König, Inke R., Schmid, Sebastian M., Wilms, Britta, Klein, Christine, Brüggemann, Norbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829299/ https://www.ncbi.nlm.nih.gov/pubmed/33505346 http://dx.doi.org/10.3389/fneur.2020.592104

Ejemplares similares

An omics-based strategy using coenzyme Q10 in patients with Parkinson’s disease: concept evaluation in a double-blind randomized placebo-controlled parallel group trial
por: Prasuhn, Jannik, et al.
Publicado: (2019)

Relationship between brain iron deposition and mitochondrial dysfunction in idiopathic Parkinson’s disease
por: Prasuhn, Jannik, et al.
Publicado: (2022)

Genotype-driven therapeutic developments in Parkinson’s disease
por: Prasuhn, Jannik, et al.
Publicado: (2021)

Gene Therapeutic Approaches for the Treatment of Mitochondrial Dysfunction in Parkinson’s Disease
por: Prasuhn, Jannik, et al.
Publicado: (2021)

Applicability of optical coherence tomography angiography (OCTA) imaging in Parkinson’s disease
por: Lauermann, Jost L., et al.
Publicado: (2021)

Neuroimaging Methods to Map In Vivo Changes of OXPHOS and Oxidative Stress in Neurodegenerative Disorders
por: Prasuhn, Jannik, et al.
Publicado: (2022)

Depressive symptoms in Parkinson’s disease are insufficiently but more often treated than in other chronic conditions
por: Usnich, Tatiana, et al.
Publicado: (2023)

A machine learning-based classification approach on Parkinson’s disease diffusion tensor imaging datasets
por: Prasuhn, Jannik, et al.
Publicado: (2020)

Iron- and Neuromelanin-Weighted Neuroimaging to Study Mitochondrial Dysfunction in Patients with Parkinson’s Disease
por: Pizarro-Galleguillos, Benjamin Matis, et al.
Publicado: (2022)

Neuroinflammation and Mitochondrial Dysfunction in Parkinson’s Disease: Connecting Neuroimaging with Pathophysiology
por: Pizarro-Galleguillos, Benjamin Matís, et al.
Publicado: (2023)

Lifestyle factors and clinical severity of Parkinson’s disease
por: Gabbert, Carolin, et al.
Publicado: (2023)

K.I.S.S. Parallel Coding (lecture 2)
por: Fronze', Gabriele Gaetano
Publicado: (2018)

Transient Generalized Chorea in Influenza A Encephalopathy
por: Prasuhn, Jannik, et al.
Publicado: (2018)

Discordance in monozygotic Parkinson's disease twins – continuum or dichotomy?
por: Balck, Alexander, et al.
Publicado: (2019)

Risky behaviors and Parkinson disease: A mendelian randomization study
por: Grover, Sandeep, et al.
Publicado: (2019)

Clinical MR imaging in Parkinson’s disease: How useful is the swallow tail sign?
por: Prasuhn, Jannik, et al.
Publicado: (2021)

The Role of Rare Coding Variants in Parkinson's Disease GWAS Loci
por: Germer, Elisabeth Luisa, et al.
Publicado: (2019)

Increased Subcortical Sodium Levels in Patients with Progressive Supranuclear Palsy
por: Prasuhn, Jannik, et al.
Publicado: (2022)

Coffee, smoking and aspirin are associated with age at onset in idiopathic Parkinson’s disease
por: Gabbert, Carolin, et al.
Publicado: (2022)

Clustering of the K(+) channel GORK of Arabidopsis parallels its gating by extracellular K(+)
por: Eisenach, Cornelia, et al.
Publicado: (2014)

Preclinical efficacy of hK2 targeted [(177)Lu]hu11B6 for prostate cancer theranostics
por: Timmermand, Oskar Vilhelmsson, et al.
Publicado: (2019)

Head impulse testing in bilateral vestibulopathy in patients with genetically defined CANVAS
por: Borsche, Max, et al.
Publicado: (2022)

Pd-Based Hybrid Nanoparticles As Multimodal Theranostic Nanomedicine
por: Bellissima, Alberto, et al.
Publicado: (2023)

Genome-Edited, TH-expressing Neuroblastoma Cells as a Disease Model for Dopamine-Related Disorders: A Proof-of-Concept Study on DJ-1-deficient Parkinsonism
por: Prasuhn, Jannik, et al.
Publicado: (2018)

Validity and Prognostic Value of a Polygenic Risk Score for Parkinson’s Disease
por: Koch, Sebastian, et al.
Publicado: (2021)

T2K
por: Sanchez Nieto, Federico
Publicado: (2012)

Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism
por: Borsche, Max, et al.
Publicado: (2020)

The K$_{L}$-K$_{S}$ mass difference
por: Bijnens, J, et al.
Publicado: (1991)

On (K-Z-n) and K-Fq(t)-(t2)
por: Aisbett, Janet E, et al.
Publicado: (1985)

Integrable deformations of the $G_{k_1} \times G_{k_2}/G_{k_1+k_2}$ coset CFTs
por: Sfetsos, Konstantinos, et al.
Publicado: (2017)

Mechanisms and consequences of weight gain after deep brain stimulation of the subthalamic nucleus in patients with Parkinson’s disease
por: Steinhardt, Julia, et al.
Publicado: (2023)

Classical algebraic K-theory i.e. the functors $K_{0}, K_{1}, K_{2}$
por: Kuku, A O
Publicado: (1999)

Randomized, double-blind, placebo-controlled, parallel-group study of the effect of Lactobacillus paracasei K71 intake on salivary release of secretory immunoglobulin A
por: SAITO, Yuhi, et al.
Publicado: (2016)

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway
por: Meng, Zhipeng, et al.
Publicado: (2015)

Improving cardiac cine MRI on 3T using 2D k-t accelerated auto-calibrating parallel imaging
por: Lai, Peng, et al.
Publicado: (2014)

The biobehavior, biocompatibility and theranostic application of SPNS and Pd@Au nanoplates in rats and rabbits
por: Li, Jingchao, et al.
Publicado: (2018)

S2k guideline for diving accidents
por: Jüttner, Björn, et al.
Publicado: (2023)

The mechanisms of the pD --> $^{3}$H$_{\Lambda}$K$^{+}$ reaction
por: Komarov, V I, et al.
Publicado: (1995)

Iterative solution of equations involving K-p.d. operators
por: Chidume, C E, et al.
Publicado: (1998)

Investigation of $K^+K^-$ pairs in the effective mass region near $2m_K$
por: Adeva, B., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_djb4gteiujdglrkvunmia4rgfh