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Comparison of Canine and Feline Meningiomas Using the Apparent Diffusion Coefficient and Fractional Anisotropy

Meningiomas are the most common intracranial tumor in dogs and cats, and their surgical resection is often performed because they are present on the brain surface. Typical meningiomas show comparatively characteristic magnetic resonance imaging findings that lead to clinical diagnosis; however, it i...

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Autores principales: Wada, Masae, Hasegawa, Daisuke, Hamamoto, Yuji, Yu, Yoshihiko, Asada, Rikako, Fujiwara-Igarashi, Aki, Fujita, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829344/
https://www.ncbi.nlm.nih.gov/pubmed/33506001
http://dx.doi.org/10.3389/fvets.2020.614026
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author Wada, Masae
Hasegawa, Daisuke
Hamamoto, Yuji
Yu, Yoshihiko
Asada, Rikako
Fujiwara-Igarashi, Aki
Fujita, Michio
author_facet Wada, Masae
Hasegawa, Daisuke
Hamamoto, Yuji
Yu, Yoshihiko
Asada, Rikako
Fujiwara-Igarashi, Aki
Fujita, Michio
author_sort Wada, Masae
collection PubMed
description Meningiomas are the most common intracranial tumor in dogs and cats, and their surgical resection is often performed because they are present on the brain surface. Typical meningiomas show comparatively characteristic magnetic resonance imaging findings that lead to clinical diagnosis; however, it is necessary to capture not only macroscopic changes but also microstructural changes to devise a strategy for surgical resection and/or quality of removal. To visualize such microstructural changes, diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) have been used in human medicine. The aim of this retrospective study was to investigate the different characteristics of the apparent diffusion coefficient (ADC) from DWI and fractional anisotropy (FA) from DTI of meningioma between dogs and cats. Statistical analyses were performed to compare ADC and FA values between the intratumoral or peritumoral regions and normal-appearing white matter (NAWM) among 13 dogs (13 lesions, but 12 each in ADC and FA analysis) and six cats (seven lesions). The NAWM of cats had a significantly lower ADC and higher FA compared to dogs. Therefore, for a comparison between dogs and cats, we used ADC and FA ratios that were calculated by dividing the subject (intra- or peritumoral) ADC and FA values by those of NAWM on the contralateral side. Regarding the intratumoral region, feline meningiomas showed a significantly lower ADC ratio and higher FA ratio than canine meningiomas. This study suggested that ADC and FA may be able to distinguish a meningioma that is solid and easy to detach, like as typical feline meningiomas.
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spelling pubmed-78293442021-01-26 Comparison of Canine and Feline Meningiomas Using the Apparent Diffusion Coefficient and Fractional Anisotropy Wada, Masae Hasegawa, Daisuke Hamamoto, Yuji Yu, Yoshihiko Asada, Rikako Fujiwara-Igarashi, Aki Fujita, Michio Front Vet Sci Veterinary Science Meningiomas are the most common intracranial tumor in dogs and cats, and their surgical resection is often performed because they are present on the brain surface. Typical meningiomas show comparatively characteristic magnetic resonance imaging findings that lead to clinical diagnosis; however, it is necessary to capture not only macroscopic changes but also microstructural changes to devise a strategy for surgical resection and/or quality of removal. To visualize such microstructural changes, diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) have been used in human medicine. The aim of this retrospective study was to investigate the different characteristics of the apparent diffusion coefficient (ADC) from DWI and fractional anisotropy (FA) from DTI of meningioma between dogs and cats. Statistical analyses were performed to compare ADC and FA values between the intratumoral or peritumoral regions and normal-appearing white matter (NAWM) among 13 dogs (13 lesions, but 12 each in ADC and FA analysis) and six cats (seven lesions). The NAWM of cats had a significantly lower ADC and higher FA compared to dogs. Therefore, for a comparison between dogs and cats, we used ADC and FA ratios that were calculated by dividing the subject (intra- or peritumoral) ADC and FA values by those of NAWM on the contralateral side. Regarding the intratumoral region, feline meningiomas showed a significantly lower ADC ratio and higher FA ratio than canine meningiomas. This study suggested that ADC and FA may be able to distinguish a meningioma that is solid and easy to detach, like as typical feline meningiomas. Frontiers Media S.A. 2021-01-11 /pmc/articles/PMC7829344/ /pubmed/33506001 http://dx.doi.org/10.3389/fvets.2020.614026 Text en Copyright © 2021 Wada, Hasegawa, Hamamoto, Yu, Asada, Fujiwara-Igarashi and Fujita. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Wada, Masae
Hasegawa, Daisuke
Hamamoto, Yuji
Yu, Yoshihiko
Asada, Rikako
Fujiwara-Igarashi, Aki
Fujita, Michio
Comparison of Canine and Feline Meningiomas Using the Apparent Diffusion Coefficient and Fractional Anisotropy
title Comparison of Canine and Feline Meningiomas Using the Apparent Diffusion Coefficient and Fractional Anisotropy
title_full Comparison of Canine and Feline Meningiomas Using the Apparent Diffusion Coefficient and Fractional Anisotropy
title_fullStr Comparison of Canine and Feline Meningiomas Using the Apparent Diffusion Coefficient and Fractional Anisotropy
title_full_unstemmed Comparison of Canine and Feline Meningiomas Using the Apparent Diffusion Coefficient and Fractional Anisotropy
title_short Comparison of Canine and Feline Meningiomas Using the Apparent Diffusion Coefficient and Fractional Anisotropy
title_sort comparison of canine and feline meningiomas using the apparent diffusion coefficient and fractional anisotropy
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829344/
https://www.ncbi.nlm.nih.gov/pubmed/33506001
http://dx.doi.org/10.3389/fvets.2020.614026
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