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In Situ-Forming Microparticles for Controlled Release of Rivastigmine: In Vitro Optimization and In Vivo Evaluation

In this work, sucrose acetate isobutyrate (SAIB) and polylactic co-glycolic acid (PLGA) were used alone or in combination as a matrix-former (MF) to prepare long-acting injectable rivastigmine (RV) in situ-forming microparticles (ISM). RV-ISM were prepared by the emulsification of an internal phase,...

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Detalles Bibliográficos
Autores principales: Haider, Mohamed, Elsayed, Ibrahim, Ahmed, Iman S., Fares, Ahmed R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829814/
https://www.ncbi.nlm.nih.gov/pubmed/33466880
http://dx.doi.org/10.3390/ph14010066

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