Serum Response Factor (SRF) Drives the Transcriptional Upregulation of the MDM4 Oncogene in HCC

SIMPLE SUMMARY: Hepatocellular carcinoma (HCC) represents the most common type of liver cancer and has a poor prognosis. Therefore, there is an urgent need for the identification of new therapeutic options. The mouse double minute homolog 4 (MDM4) gene, a known p53 inhibitor, is upregulated in most...

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Detalles Bibliográficos
Autores principales: Pellegrino, Rossella, Thavamani, Abhishek, Calvisi, Diego F., Budczies, Jan, Neumann, Ariane, Geffers, Robert, Kroemer, Jasmin, Greule, Damaris, Schirmacher, Peter, Nordheim, Alfred, Longerich, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829828/
https://www.ncbi.nlm.nih.gov/pubmed/33429878
http://dx.doi.org/10.3390/cancers13020199

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