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Modulation of Antigen Display on PapMV Nanoparticles Influences Its Immunogenicity
Background: The papaya mosaic virus (PapMV) vaccine platform is a rod-shaped nanoparticle made of the recombinant PapMV coat protein (CP) self-assembled around a noncoding single-stranded RNA (ssRNA) template. The PapMV nanoparticle induces innate immunity through stimulation of the Toll-like recept...
Autores principales: | Laliberté-Gagné, Marie-Eve, Bolduc, Marilène, Garneau, Caroline, Olivera-Ugarte, Santa-Mariela, Savard, Pierre, Leclerc, Denis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829862/ https://www.ncbi.nlm.nih.gov/pubmed/33435570 http://dx.doi.org/10.3390/vaccines9010033 |
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