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Epidemiology of Anthropometric Factors in Glioblastoma Multiforme—Literature Review
Although glioblastoma multiforme (GBM) is a widely researched cancer of the central nervous system, we still do not know its full pathophysiological mechanism and we still lack effective treatment methods as the current combination of surgery, radiotherapy, and chemotherapy does not bring about sati...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829953/ https://www.ncbi.nlm.nih.gov/pubmed/33467126 http://dx.doi.org/10.3390/brainsci11010116 |
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author | Simińska, Donata Korbecki, Jan Kojder, Klaudyna Kapczuk, Patrycja Fabiańska, Marta Gutowska, Izabela Machoy-Mokrzyńska, Anna Chlubek, Dariusz Baranowska-Bosiacka, Irena |
author_facet | Simińska, Donata Korbecki, Jan Kojder, Klaudyna Kapczuk, Patrycja Fabiańska, Marta Gutowska, Izabela Machoy-Mokrzyńska, Anna Chlubek, Dariusz Baranowska-Bosiacka, Irena |
author_sort | Simińska, Donata |
collection | PubMed |
description | Although glioblastoma multiforme (GBM) is a widely researched cancer of the central nervous system, we still do not know its full pathophysiological mechanism and we still lack effective treatment methods as the current combination of surgery, radiotherapy, and chemotherapy does not bring about satisfactory results. The median survival time for GBM patients is only about 15 months. In this paper, we present the epidemiology of central nervous system (CNS) tumors and review the epidemiological data on GBM regarding gender, age, weight, height, and tumor location. The data indicate the possible influence of some anthropometric factors on the occurrence of GBM, especially in those who are male, elderly, overweight, and/or are taller. However, this review of single and small-size epidemiological studies should not be treated as definitive due to differences in the survey methods used. Detailed epidemiological registers could help identify the main at-risk groups which could then be used as homogenous study groups in research worldwide. Such research, with less distortion from various factors, could help identify the pathomechanisms that lead to the development of GBM. |
format | Online Article Text |
id | pubmed-7829953 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-78299532021-01-26 Epidemiology of Anthropometric Factors in Glioblastoma Multiforme—Literature Review Simińska, Donata Korbecki, Jan Kojder, Klaudyna Kapczuk, Patrycja Fabiańska, Marta Gutowska, Izabela Machoy-Mokrzyńska, Anna Chlubek, Dariusz Baranowska-Bosiacka, Irena Brain Sci Review Although glioblastoma multiforme (GBM) is a widely researched cancer of the central nervous system, we still do not know its full pathophysiological mechanism and we still lack effective treatment methods as the current combination of surgery, radiotherapy, and chemotherapy does not bring about satisfactory results. The median survival time for GBM patients is only about 15 months. In this paper, we present the epidemiology of central nervous system (CNS) tumors and review the epidemiological data on GBM regarding gender, age, weight, height, and tumor location. The data indicate the possible influence of some anthropometric factors on the occurrence of GBM, especially in those who are male, elderly, overweight, and/or are taller. However, this review of single and small-size epidemiological studies should not be treated as definitive due to differences in the survey methods used. Detailed epidemiological registers could help identify the main at-risk groups which could then be used as homogenous study groups in research worldwide. Such research, with less distortion from various factors, could help identify the pathomechanisms that lead to the development of GBM. MDPI 2021-01-16 /pmc/articles/PMC7829953/ /pubmed/33467126 http://dx.doi.org/10.3390/brainsci11010116 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Simińska, Donata Korbecki, Jan Kojder, Klaudyna Kapczuk, Patrycja Fabiańska, Marta Gutowska, Izabela Machoy-Mokrzyńska, Anna Chlubek, Dariusz Baranowska-Bosiacka, Irena Epidemiology of Anthropometric Factors in Glioblastoma Multiforme—Literature Review |
title | Epidemiology of Anthropometric Factors in Glioblastoma Multiforme—Literature Review |
title_full | Epidemiology of Anthropometric Factors in Glioblastoma Multiforme—Literature Review |
title_fullStr | Epidemiology of Anthropometric Factors in Glioblastoma Multiforme—Literature Review |
title_full_unstemmed | Epidemiology of Anthropometric Factors in Glioblastoma Multiforme—Literature Review |
title_short | Epidemiology of Anthropometric Factors in Glioblastoma Multiforme—Literature Review |
title_sort | epidemiology of anthropometric factors in glioblastoma multiforme—literature review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829953/ https://www.ncbi.nlm.nih.gov/pubmed/33467126 http://dx.doi.org/10.3390/brainsci11010116 |
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