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Structure-Based Modeling of Complement C4 Mediated Neutralization of Adenovirus

Adenovirus (AdV) infection elicits a strong immune response with the production of neutralizing antibodies and opsonization by complement and coagulation factors. One anti-hexon neutralizing antibody, called 9C12, is known to activate the complement cascade, resulting in the deposition of complement...

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Detalles Bibliográficos
Autores principales: Emerson, Corey C., Stewart, Phoebe L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830055/
https://www.ncbi.nlm.nih.gov/pubmed/33467558
http://dx.doi.org/10.3390/v13010111