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Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer

An 82-year-old man suffering from prostate cancer that was scheduled for a radioreceptor-ligand therapy (RLT) presented with jaundice to our service. An abdominal ultrasound (US) revealed obstructive extrahepatic cholestasis due to a solid lesion located in the uncinate process of the pancreas. The...

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Autores principales: Sirtl, Simon, Todica, Andrei, Ilhan, Harun, Zorniak, Michal, Bartenstein, Peter, Mayerle, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830087/
https://www.ncbi.nlm.nih.gov/pubmed/33467540
http://dx.doi.org/10.3390/diagnostics11010129
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author Sirtl, Simon
Todica, Andrei
Ilhan, Harun
Zorniak, Michal
Bartenstein, Peter
Mayerle, Julia
author_facet Sirtl, Simon
Todica, Andrei
Ilhan, Harun
Zorniak, Michal
Bartenstein, Peter
Mayerle, Julia
author_sort Sirtl, Simon
collection PubMed
description An 82-year-old man suffering from prostate cancer that was scheduled for a radioreceptor-ligand therapy (RLT) presented with jaundice to our service. An abdominal ultrasound (US) revealed obstructive extrahepatic cholestasis due to a solid lesion located in the uncinate process of the pancreas. The Prostate Specific Membrane Antigen (PSMA) PET/CT prior to RLT showed multilocular PSMA positive tumor lesions in the lymph nodes, the lung and the pancreas. On request of the cancer board, an Endoscopic Ultrasound (EUS)-guided Fine-Needle Aspiration (FNA) of the pancreatic mass was performed revealing invasive pancreatic ductal adenocarcinoma incompatible with a prostate cancer metastasis leading to the diagnosis of a PSMA positive pancreatic ductal adenocarcinoma.
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spelling pubmed-78300872021-01-26 Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer Sirtl, Simon Todica, Andrei Ilhan, Harun Zorniak, Michal Bartenstein, Peter Mayerle, Julia Diagnostics (Basel) Interesting Images An 82-year-old man suffering from prostate cancer that was scheduled for a radioreceptor-ligand therapy (RLT) presented with jaundice to our service. An abdominal ultrasound (US) revealed obstructive extrahepatic cholestasis due to a solid lesion located in the uncinate process of the pancreas. The Prostate Specific Membrane Antigen (PSMA) PET/CT prior to RLT showed multilocular PSMA positive tumor lesions in the lymph nodes, the lung and the pancreas. On request of the cancer board, an Endoscopic Ultrasound (EUS)-guided Fine-Needle Aspiration (FNA) of the pancreatic mass was performed revealing invasive pancreatic ductal adenocarcinoma incompatible with a prostate cancer metastasis leading to the diagnosis of a PSMA positive pancreatic ductal adenocarcinoma. MDPI 2021-01-15 /pmc/articles/PMC7830087/ /pubmed/33467540 http://dx.doi.org/10.3390/diagnostics11010129 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Sirtl, Simon
Todica, Andrei
Ilhan, Harun
Zorniak, Michal
Bartenstein, Peter
Mayerle, Julia
Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_full Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_fullStr Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_full_unstemmed Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_short Incidental Finding of a PSMA-Positive Pancreatic Cancer in a Patient Suffering from a Metastasized PSMA-Positive Prostate Cancer
title_sort incidental finding of a psma-positive pancreatic cancer in a patient suffering from a metastasized psma-positive prostate cancer
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830087/
https://www.ncbi.nlm.nih.gov/pubmed/33467540
http://dx.doi.org/10.3390/diagnostics11010129
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