Synthesis and Biological Evaluation of (99m)Tc(I) Tricarbonyl Complexes Dual-Targeted at Tumoral Mitochondria

For effective Auger therapy of cancer, the Auger-electron emitters must be delivered to the tumor cells in close proximity to a radiosensitive cellular target. Nuclear DNA is considered the most relevant target of Auger electrons to have augmented radiotoxic effects and significant cell death. Howev...

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Detalles Bibliográficos
Autores principales: Figueiredo, Diogo, Fernandes, Célia, Silva, Francisco, Palma, Elisa, Raposinho, Paula, Belchior, Ana, Vaz, Pedro, Paulo, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830118/
https://www.ncbi.nlm.nih.gov/pubmed/33467760
http://dx.doi.org/10.3390/molecules26020441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830118/
https://www.ncbi.nlm.nih.gov/pubmed/33467760
http://dx.doi.org/10.3390/molecules26020441

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