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Efficient Production of Chimeric Hepatitis B Virus-Like Particles Bearing an Epitope of Hepatitis E Virus Capsid by Transient Expression in Nicotiana benthamiana
The core antigen of hepatitis B virus (HBcAg) is capable of self-assembly into virus-like particles (VLPs) when expressed in a number of heterologous systems. Such VLPs are potential carriers of foreign antigenic sequences for vaccine design. In this study, we evaluated the production of chimeric HB...
Autores principales: | Zahmanova, Gergana, Mazalovska, Milena, Takova, Katerina, Toneva, Valentina, Minkov, Ivan, Peyret, Hadrien, Lomonossoff, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830250/ https://www.ncbi.nlm.nih.gov/pubmed/33477348 http://dx.doi.org/10.3390/life11010064 |
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