Cargando…

Nicotinic cholinergic system and COVID-19: In silico identification of interactions between α7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V and SARS-CoV-2 Spike glycoproteins

SARS-CoV-2 is the coronavirus that originated in Wuhan in December 2019 and has spread globally. Studies have shown that smokers are less likely to be diagnosed with or be hospitalized for COVID-19 but, once hospitalized, have higher odds for an adverse outcome. We have previously presented the pote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lagoumintzis, George, Chasapis, Christos T., Alexandris, Nikolaos, Kouretas, Dimitrios, Tzartos, Socrates, Eliopoulos, Elias, Farsalinos, Konstantinos, Poulas, Konstantinos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830272/ https://www.ncbi.nlm.nih.gov/pubmed/33503469 http://dx.doi.org/10.1016/j.fct.2021.112009

Ejemplares similares

Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions
por: Alexandris, Nikolaos, et al.
Publicado: (2020)

Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications
por: Farsalinos, Konstantinos, et al.
Publicado: (2020)

Editorial: Nicotine and SARS-CoV-2: COVID-19 may be a disease of the nicotinic cholinergic system
por: Farsalinos, Konstantinos, et al.
Publicado: (2020)

COVID-19 and the nicotinic cholinergic system
por: Farsalinos, Konstantinos, et al.
Publicado: (2020)

Is SARS-CoV-2 Spike glycoprotein impairing macrophage function via α7-nicotinic acetylcholine receptors?
por: Tanmay, Saraiya, et al.
Publicado: (2021)

The SARS-CoV-2 Virus and the Cholinergic System: Spike Protein Interaction with Human Nicotinic Acetylcholine Receptors and the Nicotinic Agonist Varenicline
por: Carlson, Eric C., et al.
Publicado: (2023)

Electronic Nicotine Delivery Systems (ENDS) and Their Relevance in Oral Health
por: Isik Andrikopoulos, Gozde, et al.
Publicado: (2019)

Expression of a Highly Antigenic and Native-Like Folded Extracellular Domain of the Human α1 Subunit of Muscle Nicotinic Acetylcholine Receptor, Suitable for Use in Antigen Specific Therapies for Myasthenia Gravis
por: Niarchos, Athanasios, et al.
Publicado: (2013)

Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors
por: Oliveira, A. Sofia F., et al.
Publicado: (2020)

SARS-CoV-2 spike ectodomain targets α7 nicotinic acetylcholine receptors
por: O’Brien, Brittany C.V., et al.
Publicado: (2023)

Direct Proof of the In Vivo Pathogenic Role of the AChR Autoantibodies from Myasthenia Gravis Patients
por: Kordas, Gregory, et al.
Publicado: (2014)

A potential interaction between the SARS-CoV-2 spike protein and nicotinic acetylcholine receptors
por: Oliveira, A. Sofia F., et al.
Publicado: (2021)

Impact of SARS-CoV-2 spike protein on α7 nicotinic acetylcholine receptor in cells
por: Tillman, Tommy S., et al.
Publicado: (2022)

Nicotinic receptors as SARS-CoV-2 spike co-receptors?
por: Dormoy, Valérian, et al.
Publicado: (2022)

Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models
por: Kryukova, Elena V., et al.
Publicado: (2018)

Neural circuits and nicotinic acetylcholine receptors mediate the cholinergic regulation of midbrain dopaminergic neurons and nicotine dependence
por: Xiao, Cheng, et al.
Publicado: (2019)

The controversial effect of smoking and nicotine in SARS-CoV-2 infection
por: Salehi, Zahra, et al.
Publicado: (2023)

Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine
por: Schapira, Matthieu, et al.
Publicado: (2002)

Patterns of flavored e-cigarette use among adult vapers in the USA: an online cross-sectional survey of 69,233 participants
por: Farsalinos, Konstantinos, et al.
Publicado: (2023)

EDITORIAL: Nicotine and the Nicotinic Cholinergic System in Health and Disease
por: Pogun, Sakire
Publicado: (2018)

Nicotine absorption from electronic cigarette use: comparison between experienced consumers (vapers) and naïve users (smokers)
por: Farsalinos, Konstantinos E., et al.
Publicado: (2015)

Assessing the Direct Binding of Ark-Like E3 RING Ligases to Ubiquitin and Its Implication on Their Protein Interaction Network
por: Mintis, Dimitris G., et al.
Publicado: (2020)

Corrigendum: Nicotine absorption from electronic cigarette use: comparison between experienced consumers (vapers) and naïve users (smokers)
por: Farsalinos, Konstantinos E., et al.
Publicado: (2015)

The flavoring and not the nicotine content is a decisive factor for the effects of refill liquids of electronic cigarette on the redox status of endothelial cells
por: Kerasioti, Efthalia, et al.
Publicado: (2020)

Knowledge and Perceptions about Nicotine, Nicotine Replacement Therapies and Electronic Cigarettes among Healthcare Professionals in Greece
por: Moysidou, Anastasia, et al.
Publicado: (2016)

Neurocircuitry of the nicotinic cholinergic system
por: Bertrand, Daniel
Publicado: (2010)

Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence
por: Zuo, Lingjun, et al.
Publicado: (2016)

Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19
por: Angelopoulou, Athina, et al.
Publicado: (2020)

Nicotine Levels and Presence of Selected Tobacco-Derived Toxins in Tobacco Flavoured Electronic Cigarette Refill Liquids
por: Farsalinos, Konstantinos E., et al.
Publicado: (2015)

Association of Health Status and Nicotine Consumption with SARS-CoV-2 positivity rates
por: Duszynski, Thomas J., et al.
Publicado: (2021)

Nicotine has no significant cytoprotective activity against SARS-CoV-2 infection
por: Zheng, Fang, et al.
Publicado: (2022)

Nicotinic acetylcholine receptors and cancer
por: DANG, NINGNING, et al.
Publicado: (2016)

A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
por: Yuan, Meng, et al.
Publicado: (2020)

Regulation in the face of uncertainty: the evidence on electronic nicotine delivery systems (e-cigarettes)
por: Farsalinos, Konstantinos E, et al.
Publicado: (2015)

α7 Nicotinic Acetylcholine Receptor-Specific Antibody Induces Inflammation and Amyloid β(42) Accumulation in the Mouse Brain to Impair Memory
por: Lykhmus, Olena, et al.
Publicado: (2015)

Pathogenesis of Abdominal Aortic Aneurysms: Role of Nicotine and Nicotinic Acetylcholine Receptors
por: Li, Zong-Zhuang, et al.
Publicado: (2012)

An Overview on the Effect of Neonicotinoid Insecticides on Mammalian Cholinergic Functions through the Activation of Neuronal Nicotinic Acetylcholine Receptors
por: Houchat, Jean-Noël, et al.
Publicado: (2020)

The Oncogenic Functions of Nicotinic Acetylcholine Receptors
por: Zhao, Yue
Publicado: (2016)

Nicotinic acetylcholine receptors modulate osteoclastogenesis
por: Mandl, Peter, et al.
Publicado: (2016)

Neuronal and Extraneuronal Nicotinic Acetylcholine Receptors
por: Zoli, Michele, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_k79v7166tdpakjs6bk8umdgf8n