Emerging Roles of Protease-Activated Receptors (PARs) in the Modulation of Synaptic Transmission and Plasticity

Protease-activated receptors (PARs) are a class of G protein-coupled receptors (GPCRs) with a unique mechanism of activation, prompted by a proteolytic cleavage in their N-terminal domain that uncovers a tethered ligand, which binds and stimulates the same receptor. PARs subtypes (PAR1-4) have well-...

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Detalles Bibliográficos
Autores principales: Price, Rachel, Mercuri, Nicola Biagio, Ledonne, Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830300/
https://www.ncbi.nlm.nih.gov/pubmed/33467143
http://dx.doi.org/10.3390/ijms22020869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830300/
https://www.ncbi.nlm.nih.gov/pubmed/33467143
http://dx.doi.org/10.3390/ijms22020869

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