Engineered Phage Endolysin Eliminates Gardnerella Biofilm without Damaging Beneficial Bacteria in Bacterial Vaginosis Ex Vivo

Bacterial vaginosis is characterized by an imbalance of the vaginal microbiome and a characteristic biofilm formed on the vaginal epithelium, which is initiated and dominated by Gardnerella bacteria, and is frequently refractory to antibiotic treatment. We investigated endolysins of the type 1,4-bet...

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Detalles Bibliográficos
Autores principales: Landlinger, Christine, Tisakova, Lenka, Oberbauer, Vera, Schwebs, Timo, Muhammad, Abbas, Latka, Agnieszka, Van Simaey, Leen, Vaneechoutte, Mario, Guschin, Alexander, Resch, Gregory, Swidsinski, Sonja, Swidsinski, Alexander, Corsini, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830407/
https://www.ncbi.nlm.nih.gov/pubmed/33435575
http://dx.doi.org/10.3390/pathogens10010054

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