Quinacrine, an Antimalarial Drug with Strong Activity Inhibiting SARS-CoV-2 Viral Replication In Vitro

Quinacrine (Qx), a molecule used as an antimalarial, has shown anticancer, antiprion, and antiviral activity. The most relevant antiviral activities of Qx are related to its ability to raise pH in acidic organelles, diminishing viral enzymatic activity for viral cell entry, and its ability to bind t...

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Detalles Bibliográficos
Autores principales: Salas Rojas, Mónica, Silva Garcia, Raúl, Bini, Estela, Pérez de la Cruz, Verónica, León Contreras, Juan Carlos, Hernández Pando, Rogelio, Bastida Gonzalez, Fernando, Davila-Gonzalez, Eduardo, Orozco Morales, Mario, Gamboa Domínguez, Armando, Sotelo, Julio, Pineda, Benjamín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830524/
https://www.ncbi.nlm.nih.gov/pubmed/33477376
http://dx.doi.org/10.3390/v13010121

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