Cargando…

Neuronal Dopamine D3 Receptors: Translational Implications for Preclinical Research and CNS Disorders

Dopamine (DA), as one of the major neurotransmitters in the central nervous system (CNS) and periphery, exerts its actions through five types of receptors which belong to two major subfamilies such as D1-like (i.e., D1 and D5 receptors) and D2-like (i.e., D2, D3 and D4) receptors. Dopamine D3 recept...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kiss, Béla, Laszlovszky, István, Krámos, Balázs, Visegrády, András, Bobok, Amrita, Lévay, György, Lendvai, Balázs, Román, Viktor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830622/ https://www.ncbi.nlm.nih.gov/pubmed/33466844 http://dx.doi.org/10.3390/biom11010104

Ejemplares similares

Potential Mechanisms for Why Not All Antipsychotics Are Able to Occupy Dopamine D(3) Receptors in the Brain in vivo
por: Kiss, Béla, et al.
Publicado: (2022)

Preclinical pharmacodynamic and pharmacokinetic characterization of the major metabolites of cariprazine
por: Kiss, Béla, et al.
Publicado: (2019)

Response-related sensorimotor rhythms under scopolamine and MK-801 exposures in the touchscreen visual discrimination test in rats
por: Kostyalik, Diána, et al.
Publicado: (2022)

Disrupted Social Hierarchy in Prenatally Valproate-Exposed Autistic-Like Rats
por: Pelsőczi, Péter, et al.
Publicado: (2020)

Intranasal Oxytocin Improves Social Behavior in Laboratory Beagle Dogs (Canis familiaris) Using a Custom-Made Social Test Battery
por: Turcsán, Borbála, et al.
Publicado: (2022)

Cariprazine alleviates core behavioral deficits in the prenatal valproic acid exposure model of autism spectrum disorder
por: Román, Viktor, et al.
Publicado: (2021)

Converging Evidence on D-Amino Acid Oxidase–Dependent Enhancement of Hippocampal Firing Activity and Passive Avoidance Learning in Rats
por: Nagy, Lili Veronika, et al.
Publicado: (2020)

Contribution of analog signaling to neurotransmitter interactions and behavior: Role of transporter‐mediated nonquantal dopamine release
por: Román, Viktor, et al.
Publicado: (2021)

Purkinje cell number-correlated cerebrocerebellar circuit anomaly in the valproate model of autism
por: Spisák, Tamás, et al.
Publicado: (2019)

Safety and Tolerability of Cariprazine in Patients with Schizophrenia: A Pooled Analysis of Eight Phase II/III Studies
por: Barabássy, Ágota, et al.
Publicado: (2021)

Quantum Mechanical Modeling: A Tool for the Understanding of Enzyme Reactions
por: Náray-Szabó, Gábor, et al.
Publicado: (2013)

Cariprazine Safety in Adolescents and the Elderly: Analyses of Clinical Study Data
por: Szatmári, Balázs, et al.
Publicado: (2020)

The novel antipsychotic cariprazine stabilizes gamma oscillations in rat hippocampal slices
por: Meier, Maria A., et al.
Publicado: (2020)

Linking PANSS negative symptom scores with the Clinical Global Impressions Scale: understanding negative symptom scores in schizophrenia
por: Leucht, Stefan, et al.
Publicado: (2019)

Cariprazine, A Broad-Spectrum Antipsychotic for the Treatment of Schizophrenia: Pharmacology, Efficacy, and Safety
por: Laszlovszky, István, et al.
Publicado: (2021)

Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson’s disease
por: Goggi, Julian L., et al.
Publicado: (2020)

The novel atypical antipsychotic cariprazine demonstrates dopamine D(2) receptor‐dependent partial agonist actions on rat mesencephalic dopamine neuronal activity
por: Delcourte, Sarah, et al.
Publicado: (2018)

Disentangling the symptoms of schizophrenia: Network analysis in acute phase patients and in patients with predominant negative symptoms
por: Demyttenaere, Koen, et al.
Publicado: (2021)

Do budget constraints limit access to health care? Evidence from PCI treatments in Hungary
por: Kiss, András, et al.
Publicado: (2023)

Bacterial and Host Determinants of MAL Activation upon EPEC Infection: The Roles of Tir, ABRA, and FLRT3
por: Heath, Robert J. W., et al.
Publicado: (2011)

Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism
por: Nagy, J, et al.
Publicado: (2017)

Preferential binding to dopamine D(3) over D(2) receptors by cariprazine in patients with schizophrenia using PET with the D(3)/D(2) receptor ligand [(11)C]-(+)-PHNO
por: Girgis, Ragy R., et al.
Publicado: (2016)

Preclinical to Clinical Translation of CNS Transporter Occupancy of TD-9855, a Novel Norepinephrine and Serotonin Reuptake Inhibitor
por: Smith, Jacqueline AM, et al.
Publicado: (2015)

COVID-19-Related Intestinal Ischemia in A 7-Year Old Boy
por: Fadgyas, Balázs, et al.
Publicado: (2022)

Open Source Tools for Temporally Controlled Rodent Behavior Suitable for Electrophysiology and Optogenetic Manipulations
por: Solari, Nicola, et al.
Publicado: (2018)

Experimental evidence of dispersal of invasive cyprinid eggs inside migratory waterfowl
por: Lovas-Kiss, Ádám, et al.
Publicado: (2020)

Subcellular and regional localization of mRNA translation in midbrain dopamine neurons
por: Hobson, Benjamin D., et al.
Publicado: (2022)

Phenotypic variability in a Hungarian patient with the 4q21 microdeletion syndrome
por: Komlósi, Katalin, et al.
Publicado: (2015)

GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS
por: Eldar-Finkelman, Hagit, et al.
Publicado: (2011)

Up and Down γ-Synuclein Transcription in Dopamine Neurons Translates into Changes in Dopamine Neurotransmission and Behavioral Performance in Mice
por: Pavia-Collado, Rubén, et al.
Publicado: (2022)

Needle aspiration for treating iatrogenic pneumothorax after cardiac electronic device implantation: a pilot study
por: Domokos, Dominika, et al.
Publicado: (2019)

Cariprazine Exhibits Anxiolytic and Dopamine D(3) Receptor-Dependent Antidepressant Effects in the Chronic Stress Model
por: Duric, Vanja, et al.
Publicado: (2017)

Flow and heat transfer in geothermal systems: basic equations for describing and modeling geothermal phenomena and technologies
por: Toth, Aniko, et al.
Publicado: (2015)

Translation of immunomodulatory therapy to treat chronic heart failure: Preclinical studies to first in human
por: Humes, H. David, et al.
Publicado: (2023)

Antibiotic Consumption Patterns in European Countries May Be Associated with the Incidence of Major Carcinomas
por: Ternák, Gábor, et al.
Publicado: (2020)

The master role of polarized NIS expression in regulating iodine metabolism in the human body
por: Lévay, Bernadett, et al.
Publicado: (2023)

Parenteral Lipid-Based Nanoparticles for CNS Disorders: Integrating Various Facets of Preclinical Evaluation towards More Effective Clinical Translation
por: Ilić, Tanja, et al.
Publicado: (2023)

Three novel germ-line VHL mutations in Hungarian von Hippel-Lindau patients, including a nonsense mutation in a fifteen-year-old boy with renal cell carcinoma
por: Losonczy, Gergely, et al.
Publicado: (2013)

Cariprazine in the treatment of schizophrenia: a proof-of-concept trial
por: Durgam, Suresh, et al.
Publicado: (2016)

Molecular Mechanism for the Thermo-Sensitive Phenotype of CHO-MT58 Cell Line Harbouring a Mutant CTP:Phosphocholine Cytidylyltransferase
por: Marton, Lívia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tpfhim9oje3hfbed3f5b94bdgl