Cargando…

Synthesis of Some New Folic Acid-Based Heterocycles of Anticipated Biological Activity

To date, no fused heterocycles have been formed on folic acid molecules; for this reason, and others, our target is to synthesize new derivatives of folic acid as isolated or fused systems. Folic acid 1 reacted with ethyl pyruvate, triethyl orthoformate, ethyl chloroformate, thioformic acid hydrazid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abu Ali, Ola A., Saad, Hosam A., Al Malki, Bodor M. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830718/ https://www.ncbi.nlm.nih.gov/pubmed/33445770 http://dx.doi.org/10.3390/molecules26020368

Ejemplares similares

Synthesis and Regioselective Reaction of Some Unsymmetrical Heterocyclic Chalcone Derivatives and Spiro Heterocyclic Compounds as Antibacterial Agents
por: El-Hashash, Maher A., et al.
Publicado: (2015)

Synthesis and Biological Evaluation of Some Novel Thiazole-Based Heterocycles as Potential Anticancer and Antimicrobial Agents
por: Abu-Melha, Sraa, et al.
Publicado: (2019)

Synthesis, reactions and biological activity of some new bis-heterocyclic ring compounds containing sulphur atom
por: Mabkhot, Yahia Nasser, et al.
Publicado: (2013)

The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
por: Al-Amiery, Ahmed A., et al.
Publicado: (2011)

Utilization of Cyanoacetohydrazide and Oxadiazolyl Acetonitrile in the Synthesis of Some New Cytotoxic Heterocyclic Compounds
por: Shaker, Soheir A., et al.
Publicado: (2016)

Heterocyclic Substitutions Greatly Improve Affinity and Stability of Folic Acid towards FRα. an In Silico Insight
por: Al-Thiabat, Mohammad G., et al.
Publicado: (2021)

Synthesis and Anticancer Activity of Some New S-Glycosyl and S-Alkyl 1,2,4-Triazinone Derivatives
por: Saad, Hosam A., et al.
Publicado: (2011)

Facile Synthesis and Antimicrobial Evaluation of Some New Heterocyclic Compounds Incorporating a Biologically Active Sulfamoyl Moiety
por: Darwish, Elham S.
Publicado: (2014)

Synthesis and Reactions of Some New Heterocyclic Carbohydrazides and Related Compounds as Potential Anticancer Agents
por: Mansour, Abdel Kader, et al.
Publicado: (2003)

Synthesis and Antimicrobial Evaluation of Some Heterocyclic Chalcone Derivatives
por: Hamada, Nagwa Mohamed Mahrous, et al.
Publicado: (2011)

Synthesis, Molecular Docking Analysis and in Vitro Biological Evaluation of Some New Heterocyclic Scaffolds-Based Indole Moiety as Possible Antimicrobial Agents
por: Hassan, Entesar A., et al.
Publicado: (2022)

Synthesis and Structure-Activity Relationship of Some New Thiophene-Based Heterocycles as Potential Antimicrobial Agents
por: Mabkhot, Yahia Nasser, et al.
Publicado: (2016)

Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents
por: Azab, Mohamed E., et al.
Publicado: (2015)

Aminoacids in the Synthesis of Heterocyclic Systems: The Synthesis of Triazinoquinazolinones, Triazepinoquinazolinones and Triazocinoquinazolinones of Potential Biological Interest
por: El-Sharief, A.M.Sh., et al.
Publicado: (2001)

Synthesis and Analgesic Activity of Some New Pyrazoles and Triazoles Bearing a 6,8-Dibromo-2-methylquinazoline Moiety
por: Saad, Hosam A., et al.
Publicado: (2011)

Synthesis and Analysis of Some Bis-Heterocyclic Compounds Containing Sulphur
por: Mabkhoot, Yahia Nasser
Publicado: (2009)

Synthesis and Biological Evaluation of Some New Coumarin Derivatives
por: Al-Haiza, M.A., et al.
Publicado: (2003)

Microwave Assisted Synthesis of Some New Fused 1,2,4-Triazines Bearing Thiophene Moieties With Expected Pharmacological Activity
por: Saad, Hosam A., et al.
Publicado: (2011)

Synthesis, characterization, in silico molecular docking, and antibacterial activities of some new nitrogen-heterocyclic analogues based on a p-phenolic unit
por: Hussein, Abdel Haleem M., et al.
Publicado: (2022)

Microwave Assisted Synthesis of Some New Heterocyclic Spiro-Derivatives with Potential Antimicrobial and Antioxidant Activity
por: Youssef, Mohamed Mohamed, et al.
Publicado: (2010)

Cancer chemotherapy: targeting folic acid synthesis
por: Hagner, Nicole, et al.
Publicado: (2010)

Heterocycles 38. Biocatalytic Synthesis of New Heterocyclic Mannich Bases and Derivatives
por: Leonte, Denisa, et al.
Publicado: (2015)

Synthesis of New Polyfused Heterocycles of Biological Importance by Means of Pd(0) Catalysis
por: Hajós, Gy., et al.
Publicado: (2003)

The Use of 4-(3,4-Dichlorophenyl)-4-Oxo-2-(4-Antipyrinyl)-Butanoic Acid in the Preparation of Some New Heterocyclic Compounds With Expected Biological Activity
por: Sayed, G.H., et al.
Publicado: (2003)

Synthesis of Novel Heterocyclic Ferrocenyl Chalcones and Their Biological Evaluation
por: Alsina-Sánchez, Ámbar M., et al.
Publicado: (2023)

Synthesis and characterization of Zinc/Chitosan-Folic acid complex
por: Bandara, Subhani, et al.
Publicado: (2018)

Synthesis and Inhibitory Effect of Some Indole‐Pyrimidine Based Hybrid Heterocycles on α‐Glucosidase and α‐Amylase as Potential Hypoglycemic Agents
por: Badria, Farid A., et al.
Publicado: (2019)

Novel amides of mycophenolic acid and some heterocyclic derivatives as immunosuppressive agents
por: Walczak, Juliusz Maksymilian, et al.
Publicado: (2022)

Synthesis and Selective Cytotoxic Activities on Rhabdomyosarcoma and Noncancerous Cells of Some Heterocyclic Chalcones
por: Do, Tuong-Ha, et al.
Publicado: (2016)

Synthesis and Antibacterial Activity of Some Heterocyclic Chalcone Analogues Alone and in Combination with Antibiotics
por: Tran, Thanh-Dao, et al.
Publicado: (2012)

Synthesis of Some Novel Fused Pyrimido[4″,5″:5′,6′]-[1,2,4]triazino[3′,4′:3,4] [1,2,4]triazino[5,6-b]indoles with Expected Anticancer Activity
por: Ali, Rania S., et al.
Publicado: (2018)

Synthesis and Antibacterial Activity of Novel Curcumin Derivatives Containing Heterocyclic Moiety
por: A. Hamed, Othman, et al.
Publicado: (2013)

Azides in the Synthesis of Various Heterocycles
por: Nayl, AbdElAziz A., et al.
Publicado: (2022)

Synthesis and Antiproliferative Activity of Novel Heterocyclic Glycyrrhetinic Acid Derivatives
por: Alho, Daniela P. S., et al.
Publicado: (2019)

Synthesis, structure, and biological activity of novel heterocyclic sulfonyl-carboximidamides
por: Gobis, Katarzyna, et al.
Publicado: (2013)

Synthesis and Biological Activity Evaluation of Novel Heterocyclic Pleuromutilin Derivatives
por: Yi, Yunpeng, et al.
Publicado: (2017)

Graphene oxide immobilized 2-morpholinoethanamine as a versatile acid–base catalyst for synthesis of some heterocyclic compounds and molecular docking study
por: Amiri-Zirtol, Leila, et al.
Publicado: (2023)

Synthesis and Broad-Spectrum Antiviral Activity of Some Novel Benzo-Heterocyclic Amine Compounds
por: Zhang, Da-Jun, et al.
Publicado: (2014)

Synthesis and Characterization of Some New 4-Hydroxy-coumarin Derivatives
por: Al-Majedy, Yasameen K., et al.
Publicado: (2014)

Design, Synthesis, and Biological Evaluation of Novel Nitrogen Heterocycle-Containing Ursolic Acid Analogs as Antitumor Agents
por: Wang, Wenzhi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rg2ibcsnb7dgkmq25m690hdfaq