Studies on the Efficacy, Potential Cardiotoxicity and Monkey Pharmacokinetics of GLP-26 as a Potent Hepatitis B Virus Capsid Assembly Modulator

While treatment options are available for hepatitis B virus (HBV), there is currently no cure. Anti-HBV nucleoside analogs and interferon-alpha 2b rarely clear HBV covalently closed circular DNA (cccDNA), requiring lifelong treatment. Recently, we identified GLP-26, a glyoxamide derivative which mod...

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Detalles Bibliográficos
Autores principales: Hurwitz, Selwyn J., McBrearty, Noreen, Arzumanyan, Alla, Bichenkov, Eugene, Tao, Sijia, Bassit, Leda, Chen, Zhe, Kohler, James J., Amblard, Franck, Feitelson, Mark A., Schinazi, Raymond F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830897/
https://www.ncbi.nlm.nih.gov/pubmed/33467678
http://dx.doi.org/10.3390/v13010114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830897/
https://www.ncbi.nlm.nih.gov/pubmed/33467678
http://dx.doi.org/10.3390/v13010114

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