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Studies on the Efficacy, Potential Cardiotoxicity and Monkey Pharmacokinetics of GLP-26 as a Potent Hepatitis B Virus Capsid Assembly Modulator

While treatment options are available for hepatitis B virus (HBV), there is currently no cure. Anti-HBV nucleoside analogs and interferon-alpha 2b rarely clear HBV covalently closed circular DNA (cccDNA), requiring lifelong treatment. Recently, we identified GLP-26, a glyoxamide derivative which mod...

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Detalles Bibliográficos
Autores principales:	Hurwitz, Selwyn J., McBrearty, Noreen, Arzumanyan, Alla, Bichenkov, Eugene, Tao, Sijia, Bassit, Leda, Chen, Zhe, Kohler, James J., Amblard, Franck, Feitelson, Mark A., Schinazi, Raymond F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830897/ https://www.ncbi.nlm.nih.gov/pubmed/33467678 http://dx.doi.org/10.3390/v13010114

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