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P21-activated kinase 1 mediates angiotensin II-induced differentiation of human atrial fibroblasts via the JNK/c-Jun pathway
Cardiac fibrosis is a common pathophysiological condition involved in numerous types of cardiovascular disease. The renin-angiotensin system, particularly angiotensin II (AngII), serves an important role in cardiac fibrosis and remodeling. Furthermore, p21-activated kinase 1 (PAK1) is a highly conse...
Autores principales: | Zhou, Yafei, Xie, Ying, Li, Tao, Zhang, Peng, Chen, Tangting, Fan, Zhongcai, Tan, Xiaoqiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830933/ https://www.ncbi.nlm.nih.gov/pubmed/33495806 http://dx.doi.org/10.3892/mmr.2021.11846 |
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