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P21-activated kinase 1 mediates angiotensin II-induced differentiation of human atrial fibroblasts via the JNK/c-Jun pathway

Cardiac fibrosis is a common pathophysiological condition involved in numerous types of cardiovascular disease. The renin-angiotensin system, particularly angiotensin II (AngII), serves an important role in cardiac fibrosis and remodeling. Furthermore, p21-activated kinase 1 (PAK1) is a highly conse...

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Detalles Bibliográficos
Autores principales: Zhou, Yafei, Xie, Ying, Li, Tao, Zhang, Peng, Chen, Tangting, Fan, Zhongcai, Tan, Xiaoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830933/
https://www.ncbi.nlm.nih.gov/pubmed/33495806
http://dx.doi.org/10.3892/mmr.2021.11846

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