Cargando…

Repetitive Traumatic Brain Injury Causes Neuroinflammation before Tau Pathology in Adolescent P301S Mice

Repetitive closed head injury (rCHI) is commonly encountered in young athletes engaged in contact and collision sports. Traumatic brain injury (TBI) including rCHI has been reported to be an important risk factor for several tauopathies in studies of adult humans and animals. However, the link betwe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Izzy, Saef, Brown-Whalen, Alexander, Yahya, Taha, Sarro-Schwartz, Aliyah, Jin, Gina, Chung, Joon Yong, Lule, Sevda, Morsett, Liza M., Alquraini, Ali, Wu, Limin, Hickman, Suzanne E., Whalen, Michael J., El Khoury, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831108/ https://www.ncbi.nlm.nih.gov/pubmed/33477535 http://dx.doi.org/10.3390/ijms22020907

Ejemplares similares

Time-Dependent Changes in Microglia Transcriptional Networks Following Traumatic Brain Injury
por: Izzy, Saef, et al.
Publicado: (2019)

Quercetagitrin Inhibits Tau Accumulation and Reverses Neuroinflammation and Cognitive Deficits in P301S-Tau Transgenic Mice
por: Zhong, Suyue, et al.
Publicado: (2023)

Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice
por: Ozcelik, Sefika, et al.
Publicado: (2013)

Comorbidities and Age Are Associated With Persistent COVID-19 PCR Positivity
por: Aldhaeefi, Mohammed, et al.
Publicado: (2021)

Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy
por: Theunis, Clara, et al.
Publicado: (2013)

Methylene Blue Reduced Abnormal Tau Accumulation in P301L Tau Transgenic Mice
por: Hosokawa, Masato, et al.
Publicado: (2012)

Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice
por: Ohia-Nwoko, Odochi, et al.
Publicado: (2014)

Piericidin A Aggravates Tau Pathology in P301S Transgenic Mice
por: Höllerhage, Matthias, et al.
Publicado: (2014)

Fyn depletion ameliorates tau(P301L)-induced neuropathology
por: Liu, Guanghao, et al.
Publicado: (2020)

Levosimendan inhibits disulfide tau oligomerization and ameliorates tau pathology in Tau(P301L)-BiFC mice
por: Lim, Sungsu, et al.
Publicado: (2023)

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons
por: Rodríguez-Martín, Teresa, et al.
Publicado: (2016)

Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice
por: Hoffmann, Nadine A, et al.
Publicado: (2013)

Correction: Piericidin A Aggravates Tau Pathology in P301S Transgenic Mice
Publicado: (2015)

Altered sleep and EEG power in the P301S Tau transgenic mouse model
por: Holth, Jerrah K., et al.
Publicado: (2017)

Sex-Related Motor Deficits in the Tau-P301L Mouse Model
por: Camargo, Luana Cristina, et al.
Publicado: (2021)

Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice
por: Bi, Mian, et al.
Publicado: (2011)

Biochemical Distribution of Tau Protein in Synaptosomal Fraction of Transgenic Mice Expressing Human P301L Tau
por: Sahara, Naruhiko, et al.
Publicado: (2014)

Tau Protein Modulates Perineuronal Extracellular Matrix Expression in the TauP301L-acan Mouse Model
por: Schmidt, Sophie, et al.
Publicado: (2022)

Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau
por: Schweighauser, Manuel, et al.
Publicado: (2023)

MON-301 Long-Acting SSA Treatment Patterns in Sweden From 2005 to 2017: A Nationwide Study
por: Olsson, Daniel S, et al.
Publicado: (2020)

Human TAU(P301L) overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain
por: Cosacak, Mehmet I., et al.
Publicado: (2017)

Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning
por: Eckenweber, Florian, et al.
Publicado: (2020)

The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice
por: Di, Jing, et al.
Publicado: (2021)

Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates
por: Brelstaff, Jack H., et al.
Publicado: (2021)

Antisense Oligonucleotide-Mediated Reduction of HDAC6 Does Not Reduce Tau Pathology in P301S Tau Transgenic Mice
por: Valencia, Antonio, et al.
Publicado: (2021)

Repetitive Questioning II
por: Hamdy, R. C., et al.
Publicado: (2018)

Long-Term In Vivo Imaging of Fibrillar Tau in the Retina of P301S Transgenic Mice
por: Schön, Christian, et al.
Publicado: (2012)

Tauopathy-induced retinal dysfunction in the P301S mutant human tau transgenic mouse
por: Mazzaro, Nadia, et al.
Publicado: (2013)

Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord
por: Macdonald, Jennifer A., et al.
Publicado: (2019)

Spreading of P301S Aggregated Tau Investigated in Organotypic Mouse Brain Slice Cultures
por: Korde, Dhwani S., et al.
Publicado: (2022)

The impact of pimavanserin on psychotic phenotypes and tau phosphorylation in the P301L/COMT– and rTg(P301L)4510 mouse models of Alzheimer's disease
por: Jimenez, Heidy, et al.
Publicado: (2022)

Correction to: The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice
por: Di, Jing, et al.
Publicado: (2021)

Repetitive Questioning Exasperates Caregivers
por: Hamdy, R. C., et al.
Publicado: (2018)

Longitudinal PET studies of mGluR5 in FXS using an FMR1 knockout mouse model
por: Afshar, Sepideh, et al.
Publicado: (2022)

Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity
por: d’Abramo, Cristina, et al.
Publicado: (2013)

Differential Effects of Human P301L Tau Expression in Young versus Aged Mice
por: Hunsberger, Holly C., et al.
Publicado: (2021)

Development of P301S tau seeded organotypic hippocampal slice cultures to study potential therapeutics
por: McCarthy, James M., et al.
Publicado: (2021)

Alteration in the Synaptic and Extrasynaptic Organization of AMPA Receptors in the Hippocampus of P301S Tau Transgenic Mice
por: Alfaro-Ruiz, Rocio, et al.
Publicado: (2022)

Glimepiride mitigates tauopathy and neuroinflammation in P301S transgenic mice: role of AKT/GSK3β signaling
por: Zaki, Mennatallah O., et al.
Publicado: (2022)

The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice
por: Brelstaff, Jack, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jlbp9ajt80lnn8lacap7anv48c