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Mitochondrial haplogroup G is associated with nonalcoholic fatty liver disease, while haplogroup A mitigates the effects of PNPLA3

OBJECTIVES: Mitochondrial dysfunction plays a pivotal role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). We hypothesized that mitochondrial DNA (mtDNA) haplogroups affect the risk of NAFLD in Han Chinese patients and interact with PNPLA3 genotypes. DESIGN: NAFLD and control patien...

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Detalles Bibliográficos
Autores principales:	Gusdon, Aaron M., Hui, You, Chen, Jing, Mathews, Clayton E., Qu, Shen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831202/ https://www.ncbi.nlm.nih.gov/pubmed/33532620 http://dx.doi.org/10.1002/edm2.187

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