SuperTAD: robust detection of hierarchical topologically associated domains with optimized structural information

Topologically associating domains (TADs) are the organizational units of chromosome structures. TADs can contain TADs, thus forming a hierarchy. TAD hierarchies can be inferred from Hi-C data through coding trees. However, the current method for computing coding trees is not optimal. In this paper,...

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Detalles Bibliográficos
Autores principales: Zhang, Yu Wei, Wang, Meng Bo, Li, Shuai Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831269/
https://www.ncbi.nlm.nih.gov/pubmed/33494803
http://dx.doi.org/10.1186/s13059-020-02234-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831269/
https://www.ncbi.nlm.nih.gov/pubmed/33494803
http://dx.doi.org/10.1186/s13059-020-02234-6

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