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SuperTAD: robust detection of hierarchical topologically associated domains with optimized structural information
Topologically associating domains (TADs) are the organizational units of chromosome structures. TADs can contain TADs, thus forming a hierarchy. TAD hierarchies can be inferred from Hi-C data through coding trees. However, the current method for computing coding trees is not optimal. In this paper,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831269/ https://www.ncbi.nlm.nih.gov/pubmed/33494803 http://dx.doi.org/10.1186/s13059-020-02234-6 |