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Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells

CK2 is a Ser/Thr protein kinase overexpressed in many cancers. It is usually present in cells as a tetrameric enzyme, composed of two catalytic (α or α’) and two regulatory (β) subunits, but it is active also in its monomeric form, and the specific role of the different isoforms is largely unknown....

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Detalles Bibliográficos
Autores principales: Zonta, Francesca, Borgo, Christian, Quezada Meza, Camila Paz, Masgras, Ionica, Rasola, Andrea, Salvi, Mauro, Pinna, Lorenzo A., Ruzzene, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831337/
https://www.ncbi.nlm.nih.gov/pubmed/33477590
http://dx.doi.org/10.3390/cells10010181

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