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Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells
CK2 is a Ser/Thr protein kinase overexpressed in many cancers. It is usually present in cells as a tetrameric enzyme, composed of two catalytic (α or α’) and two regulatory (β) subunits, but it is active also in its monomeric form, and the specific role of the different isoforms is largely unknown....
Autores principales: | Zonta, Francesca, Borgo, Christian, Quezada Meza, Camila Paz, Masgras, Ionica, Rasola, Andrea, Salvi, Mauro, Pinna, Lorenzo A., Ruzzene, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831337/ https://www.ncbi.nlm.nih.gov/pubmed/33477590 http://dx.doi.org/10.3390/cells10010181 |
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