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Implementation of Neuro-Memristive Synapse for Long-and Short-Term Bio-Synaptic Plasticity

In this paper, we propose a complex neuro-memristive synapse that exhibits the physiological acts of synaptic potentiation and depression of the human-brain. Specifically, the proposed neuromorphic synapse efficiently imitates the synaptic plasticity, especially long-term potentiation (LTP) and depr...

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Detalles Bibliográficos
Autores principales: Mannan, Zubaer I., Kim, Hyongsuk, Chua, Leon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831501/
https://www.ncbi.nlm.nih.gov/pubmed/33477650
http://dx.doi.org/10.3390/s21020644
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author Mannan, Zubaer I.
Kim, Hyongsuk
Chua, Leon
author_facet Mannan, Zubaer I.
Kim, Hyongsuk
Chua, Leon
author_sort Mannan, Zubaer I.
collection PubMed
description In this paper, we propose a complex neuro-memristive synapse that exhibits the physiological acts of synaptic potentiation and depression of the human-brain. Specifically, the proposed neuromorphic synapse efficiently imitates the synaptic plasticity, especially long-term potentiation (LTP) and depression (LTD), and short-term facilitation (STF) and depression (STD), phenomena of a biological synapse. Similar to biological synapse, the short- or long-term potentiation (STF and LTP) or depression (STD or LTD) of the memristive synapse are distinguished on the basis of time or repetition of input cycles. The proposed synapse is also designed to exhibit the effect of reuptake and neurotransmitters diffusion processes of a bio-synapse. In addition, it exhibits the distinct bio-realistic attributes, i.e., strong stimulation, exponentially decaying conductance trace of synapse, and voltage dependent synaptic responses, of a neuron. The neuro-memristive synapse is designed in SPICE and its bio-realistic functionalities are demonstrated via various simulations.
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spelling pubmed-78315012021-01-26 Implementation of Neuro-Memristive Synapse for Long-and Short-Term Bio-Synaptic Plasticity Mannan, Zubaer I. Kim, Hyongsuk Chua, Leon Sensors (Basel) Article In this paper, we propose a complex neuro-memristive synapse that exhibits the physiological acts of synaptic potentiation and depression of the human-brain. Specifically, the proposed neuromorphic synapse efficiently imitates the synaptic plasticity, especially long-term potentiation (LTP) and depression (LTD), and short-term facilitation (STF) and depression (STD), phenomena of a biological synapse. Similar to biological synapse, the short- or long-term potentiation (STF and LTP) or depression (STD or LTD) of the memristive synapse are distinguished on the basis of time or repetition of input cycles. The proposed synapse is also designed to exhibit the effect of reuptake and neurotransmitters diffusion processes of a bio-synapse. In addition, it exhibits the distinct bio-realistic attributes, i.e., strong stimulation, exponentially decaying conductance trace of synapse, and voltage dependent synaptic responses, of a neuron. The neuro-memristive synapse is designed in SPICE and its bio-realistic functionalities are demonstrated via various simulations. MDPI 2021-01-18 /pmc/articles/PMC7831501/ /pubmed/33477650 http://dx.doi.org/10.3390/s21020644 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mannan, Zubaer I.
Kim, Hyongsuk
Chua, Leon
Implementation of Neuro-Memristive Synapse for Long-and Short-Term Bio-Synaptic Plasticity
title Implementation of Neuro-Memristive Synapse for Long-and Short-Term Bio-Synaptic Plasticity
title_full Implementation of Neuro-Memristive Synapse for Long-and Short-Term Bio-Synaptic Plasticity
title_fullStr Implementation of Neuro-Memristive Synapse for Long-and Short-Term Bio-Synaptic Plasticity
title_full_unstemmed Implementation of Neuro-Memristive Synapse for Long-and Short-Term Bio-Synaptic Plasticity
title_short Implementation of Neuro-Memristive Synapse for Long-and Short-Term Bio-Synaptic Plasticity
title_sort implementation of neuro-memristive synapse for long-and short-term bio-synaptic plasticity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831501/
https://www.ncbi.nlm.nih.gov/pubmed/33477650
http://dx.doi.org/10.3390/s21020644
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