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Monosubstituted Acetophenone Thiosemicarbazones as Potent Inhibitors of Tyrosinase: Synthesis, Inhibitory Studies, and Molecular Docking

A set of 12 monosubstituted acetophenone thiosemicarbazone derivatives (TSCs) were synthesized and their inhibitory properties toward tyrosinase activity were tested. Moreover, their ability to inhibit melanogenesis in the B16F10 murine melanoma cell line was studied. In order to investigate the nat...

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Detalles Bibliográficos
Autores principales: Hałdys, Katarzyna, Goldeman, Waldemar, Anger-Góra, Natalia, Rossowska, Joanna, Latajka, Rafał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831505/
https://www.ncbi.nlm.nih.gov/pubmed/33477655
http://dx.doi.org/10.3390/ph14010074