Cargando…

Epidemiological and clinical features of COVID-19 patients in Saudi Arabia

BACKGROUND: The aim of this study is to describe the clinical and demographic characteristics of COVID-19 patients, and the risk factors associated with death in Saudi Arabia to serve as a reference to further understand this pandemic and to help in the future decisions and control of this global cr...

Descripción completa

Detalles Bibliográficos
Autores principales: Alahmari, Ahmed A., Khan, Anas A., Elganainy, Ahmed, Almohammadi, Emad L., Hakawi, Ahmed M., Assiri, Abdullah M., Jokhdar, Hani A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831680/
https://www.ncbi.nlm.nih.gov/pubmed/33743364
http://dx.doi.org/10.1016/j.jiph.2021.01.003
_version_ 1783641669374050304
author Alahmari, Ahmed A.
Khan, Anas A.
Elganainy, Ahmed
Almohammadi, Emad L.
Hakawi, Ahmed M.
Assiri, Abdullah M.
Jokhdar, Hani A.
author_facet Alahmari, Ahmed A.
Khan, Anas A.
Elganainy, Ahmed
Almohammadi, Emad L.
Hakawi, Ahmed M.
Assiri, Abdullah M.
Jokhdar, Hani A.
author_sort Alahmari, Ahmed A.
collection PubMed
description BACKGROUND: The aim of this study is to describe the clinical and demographic characteristics of COVID-19 patients, and the risk factors associated with death in Saudi Arabia to serve as a reference to further understand this pandemic and to help in the future decisions and control of this global crisis. METHODS: This multicenter, retrospective, observational, cross-sectional study was conducted on 240,474 patients with confirmed COVID-19 in Saudi Arabia. Data was collected retrospectively through the Health Electronic Surveillance Network at the Ministry of Health. Patients were classified based on their outcome as recovered, dead, or active with no definite outcome. We must specify the date period. RESULTS: As of 20th of June 2020, 79.7% of COVID-19 cases were young and middle-aged, ranging between 20–59 years. There was evidently a difference in the sex ratio, where males constituted 71.7% of cases. The majority were non-Saudi nationals, representing 54.7% of cases. Furthermore, the contraction of COVID-19 was travel-related in 45.1% of cases. Signs and symptoms were reported in 63% of cases, the most common of which were fever; 85.2%, and cough; 85%. Deaths occurred more frequently in patients 40−49 years, 50−59 years, and 60−69 years, representing 19.2%, 27.9%, and 21.3% of deaths, respectively. Additionally, the case fatality rate (CFR) was higher in older age-groups, reaching 10.1% in those ≥80 years. Moreover, the CFR of males was higher than that of females, with 0.95% and 0.62%, respectively. As for nationality, Saudis had a CFR of 0.46% versus 1.19% in non-Saudis. CONCLUSION: The total number of positive COVID-19 cases detected constitute 0.7% of the Saudi population to date. Older age, non-Saudi nationalities, being male, travelling outside Saudi Arabia, and the presence of symptoms, as opposed to being asymptomatic were considered risk factors and found to be significantly more associated with death in patients with COVID-19.
format Online
Article
Text
id pubmed-7831680
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Author(s). Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.
record_format MEDLINE/PubMed
spelling pubmed-78316802021-01-26 Epidemiological and clinical features of COVID-19 patients in Saudi Arabia Alahmari, Ahmed A. Khan, Anas A. Elganainy, Ahmed Almohammadi, Emad L. Hakawi, Ahmed M. Assiri, Abdullah M. Jokhdar, Hani A. J Infect Public Health Article BACKGROUND: The aim of this study is to describe the clinical and demographic characteristics of COVID-19 patients, and the risk factors associated with death in Saudi Arabia to serve as a reference to further understand this pandemic and to help in the future decisions and control of this global crisis. METHODS: This multicenter, retrospective, observational, cross-sectional study was conducted on 240,474 patients with confirmed COVID-19 in Saudi Arabia. Data was collected retrospectively through the Health Electronic Surveillance Network at the Ministry of Health. Patients were classified based on their outcome as recovered, dead, or active with no definite outcome. We must specify the date period. RESULTS: As of 20th of June 2020, 79.7% of COVID-19 cases were young and middle-aged, ranging between 20–59 years. There was evidently a difference in the sex ratio, where males constituted 71.7% of cases. The majority were non-Saudi nationals, representing 54.7% of cases. Furthermore, the contraction of COVID-19 was travel-related in 45.1% of cases. Signs and symptoms were reported in 63% of cases, the most common of which were fever; 85.2%, and cough; 85%. Deaths occurred more frequently in patients 40−49 years, 50−59 years, and 60−69 years, representing 19.2%, 27.9%, and 21.3% of deaths, respectively. Additionally, the case fatality rate (CFR) was higher in older age-groups, reaching 10.1% in those ≥80 years. Moreover, the CFR of males was higher than that of females, with 0.95% and 0.62%, respectively. As for nationality, Saudis had a CFR of 0.46% versus 1.19% in non-Saudis. CONCLUSION: The total number of positive COVID-19 cases detected constitute 0.7% of the Saudi population to date. Older age, non-Saudi nationalities, being male, travelling outside Saudi Arabia, and the presence of symptoms, as opposed to being asymptomatic were considered risk factors and found to be significantly more associated with death in patients with COVID-19. The Author(s). Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. 2021-04 2021-01-16 /pmc/articles/PMC7831680/ /pubmed/33743364 http://dx.doi.org/10.1016/j.jiph.2021.01.003 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Alahmari, Ahmed A.
Khan, Anas A.
Elganainy, Ahmed
Almohammadi, Emad L.
Hakawi, Ahmed M.
Assiri, Abdullah M.
Jokhdar, Hani A.
Epidemiological and clinical features of COVID-19 patients in Saudi Arabia
title Epidemiological and clinical features of COVID-19 patients in Saudi Arabia
title_full Epidemiological and clinical features of COVID-19 patients in Saudi Arabia
title_fullStr Epidemiological and clinical features of COVID-19 patients in Saudi Arabia
title_full_unstemmed Epidemiological and clinical features of COVID-19 patients in Saudi Arabia
title_short Epidemiological and clinical features of COVID-19 patients in Saudi Arabia
title_sort epidemiological and clinical features of covid-19 patients in saudi arabia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831680/
https://www.ncbi.nlm.nih.gov/pubmed/33743364
http://dx.doi.org/10.1016/j.jiph.2021.01.003
work_keys_str_mv AT alahmariahmeda epidemiologicalandclinicalfeaturesofcovid19patientsinsaudiarabia
AT khananasa epidemiologicalandclinicalfeaturesofcovid19patientsinsaudiarabia
AT elganainyahmed epidemiologicalandclinicalfeaturesofcovid19patientsinsaudiarabia
AT almohammadiemadl epidemiologicalandclinicalfeaturesofcovid19patientsinsaudiarabia
AT hakawiahmedm epidemiologicalandclinicalfeaturesofcovid19patientsinsaudiarabia
AT assiriabdullahm epidemiologicalandclinicalfeaturesofcovid19patientsinsaudiarabia
AT jokhdarhania epidemiologicalandclinicalfeaturesofcovid19patientsinsaudiarabia