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Paediatric gastric organoids as a tool for disease modelling and clinical translation

PURPOSE: Knowledge of gastric epithelial homeostasis remains incomplete, lacking human-specific models for study. This study establishes a protocol for deriving gastric epithelial organoids from paediatric gastric biopsies, providing a platform for modelling disease and developing translational ther...

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Detalles Bibliográficos
Autores principales: Jones, Brendan C., Calà, Giuseppe, De Coppi, Paolo, Giobbe, Giovanni Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831693/
https://www.ncbi.nlm.nih.gov/pubmed/33495862
http://dx.doi.org/10.1007/s00383-020-04821-x